Whole-genome sequencing to characterize monogenic and polygenic contributions in patients hospitalized with early-onset myocardial infarction

by Khera, Amit V., Chaffin, Mark, Zekavat, Seyedeh Maryam, Roselli, Carolina, Natarajan, Pradeep, Kathiresan, Sekar
Published 2020

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

by Khera, Amit V., Chaffin, Mark, Aragam, Krishna G., Haas, Mary E., Roselli, Carolina, Choi, Seung Hoan, Natarajan, Pradeep, Lander, Eric Steven, Lubitz, Steven A., Ellinor, Patrick T., Kathiresan, Sekar
Published 2020

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

by Khera, Amit V., Chaffin, Mark, Wade, Kaitlin H., Zahid, Sohail, Brancale, Joseph, Xia, Rui, Distefano, Marina, Senol-Cosar, Ozlem, Haas, Mary E., Bick, Alexander, Aragam, Krishna G., Lander, Eric Steven, Smith, George Davey, Mason-Suares, Heather, Fornage, Myriam, Lebo, Matthew, Timpson, Nicholas J., Kaplan, Lee M., Kathiresan, Sekar
Published 2020

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

by Natarajan, Pradeep, Peloso, Gina M., Zekavat, Seyedeh Maryam, Montasser, May, Ganna, Andrea, Chaffin, Mark, Khera, Amit V., Zhou, Wei, Bloom, Jonathan M., Engreitz, Jesse M., Ernst, Jason, O'Connell, Jeffrey R., Ruotsalainen, Sanni E., Alver, Maris, Manichaikul, Ani, Johnson, W. Craig, Perry, James A., Poterba, Timothy, Seed, Cotton, Surakka, Ida L., Esko, Tonu, Ripatti, Samuli, Salomaa, Veikko, Correa, Adolfo, Vasan, Ramachandran S., Kellis, Manolis, Neale, Benjamin M., Lander, Eric S., Abecasis, Goncalo, Mitchell, Braxton, Rich, Stephen S., Wilson, James G., Cupples, L. Adrienne, Rotter, Jerome I., Willer, Cristen J., Kathiresan, Sekar
Published 2020