Improving Adaptive and Memory Immune Responses of an HIV/AIDS Vaccine Candidate MVA-B by Deletion of Vaccinia Virus Genes (C6L and K7R) Blocking Interferon Signaling Pathways.

by Juan García-Arriaza, Pilar Arnáez, Carmen E Gómez, Carlos Óscar S Sorzano, Mariano Esteban
Published 2013-01-01

Immunogenic profiling in mice of a HIV/AIDS vaccine candidate (MVA-B) expressing four HIV-1 antigens and potentiation by specific gene deletions.

by Juan García-Arriaza, José Luis Nájera, Carmen E Gómez, Carlos Oscar S Sorzano, Mariano Esteban
Published 2010-01-01

Removal of the C6 Vaccinia Virus Interferon-β Inhibitor in the Hepatitis C Vaccine Candidate MVA-HCV Elicited in Mice High Immunogenicity in Spite of Reduced Host Gene Expression

by María Q. Marín, Patricia Pérez, Carmen E. Gómez, Carlos Óscar S. Sorzano, Mariano Esteban, Juan García-Arriaza
Published 2018-08-01

The biocontrol endophytic bacterium Pseudomonas fluorescens PICF7 induces systemic defense responses in aerial tissues upon colonization of olive roots

by Carmen eGómez-Lama Cabanás, Elisabetta eSchiliro`, Antonio eValverde-Corredor, Jesús eMercado-Blanco
Published 2014-09-01

Involvement of the cellular phosphatase DUSP1 in vaccinia virus infection.

by Ana Cáceres, Beatriz Perdiguero, Carmen E Gómez, Maria Victoria Cepeda, Carme Caelles, Carlos Oscar Sorzano, Mariano Esteban
Published 2013-01-01

A human multi-epitope recombinant vaccinia virus as a universal T cell vaccine candidate against influenza virus.

by Alan G Goodman, Paul P Heinen, Susana Guerra, Aneesh Vijayan, Carlos Oscar S Sorzano, Carmen E Gomez, Mariano Esteban
Published 2011-01-01

Deletion of Vaccinia Virus A40R Gene Improves the Immunogenicity of the HIV-1 Vaccine Candidate MVA-B

by Patricia Pérez, María Q. Marín, Adrián Lázaro-Frías, Carlos Óscar S. Sorzano, Carmen E. Gómez, Mariano Esteban, Juan García-Arriaza
Published 2020-02-01

A candidate HIV/AIDS vaccine (MVA-B) lacking vaccinia virus gene C6L enhances memory HIV-1-specific T-cell responses.

by Juan García-Arriaza, José Luis Nájera, Carmen E Gómez, Nolawit Tewabe, Carlos Oscar S Sorzano, Thierry Calandra, Thierry Roger, Mariano Esteban
Published 2011-01-01

Optimized Hepatitis C Virus (HCV) E2 Glycoproteins and their Immunogenicity in Combination with MVA-HCV

by María Q. Marín, Kwinten Sliepen, Juan García-Arriaza, Sylvie M. Koekkoek, Patricia Pérez, Carlos Óscar S. Sorzano, Carmen E. Gómez, Rogier W. Sanders, Mariano Esteban
Published 2020-08-01

Improving the MVA vaccine potential by deleting the viral gene coding for the IL-18 binding protein.

by Juliana Falivene, María Paula Del Médico Zajac, María Fernanda Pascutti, Ana María Rodríguez, Cynthia Maeto, Beatriz Perdiguero, Carmen E Gómez, Mariano Esteban, Gabriela Calamante, María Magdalena Gherardi
Published 2012-01-01

Innate immune sensing of modified vaccinia virus Ankara (MVA) is mediated by TLR2-TLR6, MDA-5 and the NALP3 inflammasome.

by Julie Delaloye, Thierry Roger, Quynh-Giao Steiner-Tardivel, Didier Le Roy, Marlies Knaup Reymond, Shizuo Akira, Virginie Petrilli, Carmen E Gomez, Beatriz Perdiguero, Jürg Tschopp, Giuseppe Pantaleo, Mariano Esteban, Thierry Calandra
Published 2009-06-01

Improved NYVAC-based vaccine vectors.

by Karen V Kibler, Carmen E Gomez, Beatriz Perdiguero, Shukmei Wong, Trung Huynh, Susan Holechek, William Arndt, Victoria Jimenez, Ruben Gonzalez-Sanz, Karen Denzler, Elias K Haddad, Ralf Wagner, Rafick P Sékaly, James Tartaglia, Giuseppe Pantaleo, Bertram L Jacobs, Mariano Esteban
Published 2011-01-01

Virological and immunological outcome of treatment interruption in HIV-1-infected subjects vaccinated with MVA-B.

by Miriam Rosás-Umbert, Beatriz Mothe, Marc Noguera-Julian, Rocío Bellido, Maria C Puertas, Jorge Carrillo, C Rodriguez, Núria Perez-Alvarez, Patricia Cobarsí, Carmen E Gomez, Mariano Esteban, Jose Luis Jímenez, Felipe García, Julià Blanco, Javier Martinez-Picado, Roger Paredes, Christian Brander
Published 2017-01-01

Comparison of Safety and Vector-Specific Immune Responses in Healthy and HIV-Infected Populations Vaccinated with MVA-B

by Elvira Couto, Vicenç Diaz-Brito, Beatriz Mothe, Alberto C. Guardo, Irene Fernandez, Ainoa Ugarte, Flor Etcheverry, Carmen E. Gómez, Mariano Esteban, Judit Pich, Joan Albert Arnaiz, Juan Carlos López Bernaldo de Quirós, Christian Brander, Montserrat Plana, Felipe García, Lorna Leal
Published 2019-11-01

Neuroinflammation induced by intracerebroventricular injection of microbial neuraminidase

by Pablo eGranados-Durán, Maria D. López-Ávalos, Jesús M. eGrondona, María del Carmen eGómez-Roldán, Manuel eCifuentes, Manuel eCifuentes, Margarita ePérez-Martín, Martina eÁlvarez, Fernando eRodríguez de Fonseca, Pedro eFernández-Llebrez
Published 2015-03-01

Neutrophil subtypes shape HIV-specific CD8 T-cell responses after vaccinia virus infection

by Mauro Di Pilato, Miguel Palomino-Segura, Ernesto Mejías-Pérez, Carmen E. Gómez, Andrea Rubio-Ponce, Rocco D’Antuono, Diego Ulisse Pizzagalli, Patricia Pérez, Raphael Kfuri-Rubens, Alberto Benguría, Ana Dopazo, Iván Ballesteros, Carlos Oscar S. Sorzano, Andrés Hidalgo, Mariano Esteban, Santiago F. Gonzalez
Published 2021-04-01

The Envelope-Based Fusion Antigen GP120C14K Forming Hexamer-Like Structures Triggers T Cell and Neutralizing Antibody Responses Against HIV-1

by Suresh C. Raman, Ernesto Mejías-Pérez, Carmen E. Gomez, Juan García-Arriaza, Beatriz Perdiguero, Aneesh Vijayan, Mar Pérez-Ruiz, Ana Cuervo, César Santiago, Carlos Oscar S. Sorzano, Cristina Sánchez-Corzo, Christiane Moog, Judith A. Burger, Anna Schorcht, Rogier W. Sanders, Rogier W. Sanders, José L. Carrascosa, Mariano Esteban
Published 2019-12-01

Immune Profiles Identification by Vaccinomics After MVA Immunization in Randomized Clinical Study

by Jorge Sanchez, Elena Gonçalves, Anuska Llano, Pedro Gonzáles, María Fernández-Maldonado, Annika Vogt, Angele Soria, Susana Perez, Samandhy Cedeño, Marco Antonio Fernández, Julien Nourikyan, Simon de Bernard, Carmela Ganoza, Eric Pedruzzi, Olivia Bonduelle, Beatriz Mothe, Beatriz Mothe, Carmen E. Gòmez, Mariano Esteban, Felipe Garcia, Javier R. Lama, Christian Brander, Christian Brander, Christian Brander, Behazine Combadiere
Published 2020-11-01

Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors.

by Esther D Quakkelaar, Anke Redeker, Elias K Haddad, Alexandre Harari, Stella Mayo McCaughey, Thomas Duhen, Abdelali Filali-Mouhim, Jean-Philippe Goulet, Nikki M Loof, Ferry Ossendorp, Beatriz Perdiguero, Paul Heinen, Carmen E Gomez, Karen V Kibler, David M Koelle, Rafick P Sékaly, Federica Sallusto, Antonio Lanzavecchia, Giuseppe Pantaleo, Mariano Esteban, Jim Tartaglia, Bertram L Jacobs, Cornelis J M Melief
Published 2011-02-01