Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity.

by Charles W Tran, Matthew J Gold, Carlos Garcia-Batres, Kelly Tai, Alisha R Elford, Megan E Himmel, Andrew J Elia, Pamela S Ohashi
Published 2020-01-01

831 E3 ubiquitin ligase Cbl-b deficient CD8+ T cells overcome Treg cell-mediated suppression through IFN-γ and induce robust anti-tumor immunity

by SeongJun Han, Zhe Qi Liu, Douglas Chung, Michael St Paul, Carlos Garcia-Batres, Azin Sayad, Alisha Elford, Matthew Gold, Natasha Grimshaw, Pamela Ohashi
Published 2020-11-01

Overproduction of IL-2 by Cbl-b deficient CD4+ T cells provides resistance against regulatory T cells

by SeongJun Han, Douglas C. Chung, Michael St. Paul, Zhe Qi Liu, Carlos Garcia-Batres, Alisha R. Elford, Charles W. Tran, Laurence Chapatte, Pamela S. Ohashi
Published 2020-01-01

Tumor cell expression of B7-H4 correlates with higher frequencies of tumor-infiltrating APCs and higher CXCL17 expression in human epithelial ovarian cancer

by Heather L. MacGregor, Carlos Garcia-Batres, Azin Sayad, Andrew Elia, Hal K. Berman, Aras Toker, Sarah Rachel Katz, Patricia A. Shaw, Blaise A. Clarke, Sarah Q. Crome, Celine Robert-Tissot, Marcus Q. Bernardini, Linh T. Nguyen, Pamela S. Ohashi
Published 2019-12-01