Different toll-like receptor stimuli have a profound impact on cytokines required to break tolerance and induce autoimmunity.

by Albert C C Lin, Dilan Dissanayake, Salim Dhanji, Alisha R Elford, Pamela S Ohashi
Published 2011-01-01

Peptide-pulsed dendritic cells have superior ability to induce immune-mediated tissue destruction compared to peptide with adjuvant.

by Dilan Dissanayake, Kiichi Murakami, Michael D Tran, Alisha R Elford, Douglas G Millar, Pamela S Ohashi
Published 2014-01-01

Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity.

by Charles W Tran, Matthew J Gold, Carlos Garcia-Batres, Kelly Tai, Alisha R Elford, Megan E Himmel, Andrew J Elia, Pamela S Ohashi
Published 2020-01-01

Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes.

by Nobuyuki Ono, Kiichi Murakami, Olivia Chan, Håkan Hall, Alisha R Elford, Patty Yen, Thomas Calzascia, David M Spencer, Pamela S Ohashi, Salim Dhanji
Published 2017-01-01

Overproduction of IL-2 by Cbl-b deficient CD4+ T cells provides resistance against regulatory T cells

by SeongJun Han, Douglas C. Chung, Michael St. Paul, Zhe Qi Liu, Carlos Garcia-Batres, Alisha R. Elford, Charles W. Tran, Laurence Chapatte, Pamela S. Ohashi
Published 2020-01-01

NK Cells Regulate CD8+ T Cell Mediated Autoimmunity

by Philipp A. Lang, Philipp A. Lang, Philipp A. Lang, Sarah Q. Crome, Sarah Q. Crome, Haifeng C. Xu, Haifeng C. Xu, Karl S. Lang, Karl S. Lang, Laurence Chapatte, Elissa K. Deenick, Elissa K. Deenick, Melanie Grusdat, Aleksandra A. Pandyra, Vitaly I. Pozdeev, Ruifeng Wang, Tobias A. W. Holderried, Tobias A. W. Holderried, Harvey Cantor, Andreas Diefenbach, Andreas Diefenbach, Andreas Diefenbach, Alisha R. Elford, David R. McIlwain, Mike Recher, Dieter Häussinger, Tak W. Mak, Tak W. Mak, Pamela S. Ohashi, Pamela S. Ohashi
Published 2020-02-01