Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

by Barbara Selisko, Nicolas Papageorgiou, François Ferron, Bruno Canard
Published 2018-01-01

Primer-dependent and primer-independent initiation of double stranded RNA synthesis by purified Arabidopsis RNA-dependent RNA polymerases RDR2 and RDR6.

by Anthony Devert, Nicolas Fabre, Maïna Floris, Bruno Canard, Christophe Robaglia, Patrice Crété
Published 2015-01-01

Comparative production analysis of three phlebovirus nucleoproteins under denaturing or non-denaturing conditions for crystallographic studies.

by Violaine Lantez, Karen Dalle, Rémi Charrel, Cécile Baronti, Bruno Canard, Bruno Coutard
Published 2011-01-01

Crystal structures of Lymphocytic choriomeningitis virus endonuclease domain complexed with diketo-acid ligands

by Magali Saez-Ayala, Elsie Laban Yekwa, Mauro Carcelli, Bruno Canard, Karine Alvarez, François Ferron
Published 2018-03-01

In vitro reconstitution of SARS-coronavirus mRNA cap methylation.

by Mickaël Bouvet, Claire Debarnot, Isabelle Imbert, Barbara Selisko, Eric J Snijder, Bruno Canard, Etienne Decroly
Published 2010-04-01

Correction: Reconstitution of SARS-Coronavirus mRNA Cap Methylation.

by Mickaël Bouvet, Claire Debarnot, Isabelle Imbert, Barbara Selisko, Eric J. Snijder, Bruno Canard, Etienne Decroly
Published 2010-05-01

The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity

by Natacha S. Ogando, Francois Ferron, Francois Ferron, Etienne Decroly, Bruno Canard, Clara C. Posthuma, Eric J. Snijder
Published 2019-08-01

Observation of arenavirus nucleoprotein heptamer assembly

by Nicolas Papageorgiou, Afroditi Vaitsopoulou, Awa Diop, Thi Hong Van Nguyen, Bruno Canard, Karine Alvarez, François Ferron
Published 2021-04-01

Brothers in Arms: Structure, Assembly and Function of Arenaviridae Nucleoprotein

by Nicolas Papageorgiou, Maria Spiliopoulou, Thi-Hong Van Nguyen, Afroditi Vaitsopoulou, Elsie Yekwa Laban, Karine Alvarez, Irene Margiolaki, Bruno Canard, François Ferron
Published 2020-07-01

Molecular basis for nucleotide conservation at the ends of the dengue virus genome.

by Barbara Selisko, Supanee Potisopon, Rym Agred, Stéphane Priet, Isabelle Varlet, Yann Thillier, Corinne Sallamand, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard
Published 2012-09-01

The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes.

by François Ferron, Zongli Li, Eric I Danek, Dahai Luo, Yeehwa Wong, Bruno Coutard, Violaine Lantez, Rémi Charrel, Bruno Canard, Thomas Walz, Julien Lescar
Published 2011-05-01

Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex.

by Etienne Decroly, Claire Debarnot, François Ferron, Mickael Bouvet, Bruno Coutard, Isabelle Imbert, Laure Gluais, Nicolas Papageorgiou, Andrew Sharff, Gérard Bricogne, Miguel Ortiz-Lombardia, Julien Lescar, Bruno Canard
Published 2011-05-01

Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis

by Ashleigh Shannon, Barbara Selisko, Nhung-Thi-Tuyet Le, Johanna Huchting, Franck Touret, Géraldine Piorkowski, Véronique Fattorini, François Ferron, Etienne Decroly, Chris Meier, Bruno Coutard, Olve Peersen, Bruno Canard
Published 2020-09-01

The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2'-O-methylation.

by Priscila Sutto-Ortiz, Sergey Tcherniuk, Nina Ysebaert, Pravien Abeywickrema, Mathieu Noël, Alice Decombe, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard, Dirk Roymans, Peter Rigaux, Jean-François Eléouët, Etienne Decroly
Published 2021-05-01

The N-terminal domain of the arenavirus L protein is an RNA endonuclease essential in mRNA transcription.

by Benjamin Morin, Bruno Coutard, Michaela Lelke, François Ferron, Romy Kerber, Saïd Jamal, Antoine Frangeul, Cécile Baronti, Rémi Charrel, Xavier de Lamballerie, Clemens Vonrhein, Julien Lescar, Gérard Bricogne, Stephan Günther, Bruno Canard
Published 2010-09-01

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective

by Mona Seifert, Subhas C Bera, Pauline van Nies, Robert N Kirchdoerfer, Ashleigh Shannon, Thi-Tuyet-Nhung Le, Xiangzhi Meng, Hongjie Xia, James M Wood, Lawrence D Harris, Flavia S Papini, Jamie J Arnold, Steven Almo, Tyler L Grove, Pei-Yong Shi, Yan Xiang, Bruno Canard, Martin Depken, Craig E Cameron, David Dulin
Published 2021-10-01

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family.

by Lonneke van der Linden, Laia Vives-Adrián, Barbara Selisko, Cristina Ferrer-Orta, Xinran Liu, Kjerstin Lanke, Rachel Ulferts, Armando M De Palma, Federica Tanchis, Nesya Goris, David Lefebvre, Kris De Clercq, Pieter Leyssen, Céline Lacroix, Gerhard Pürstinger, Bruno Coutard, Bruno Canard, David D Boehr, Jamie J Arnold, Craig E Cameron, Nuria Verdaguer, Johan Neyts, Frank J M van Kuppeveld
Published 2015-03-01