Structure-Based Design of Dimeric Bisbenzimidazole Inhibitors to an Emergent Trimethoprim-Resistant Type II Dihydrofolate Reductase Guides the Design of Monomeric Analogues

by Jacynthe L. Toulouse, Brahm J. Yachnin, Edward H. Ruediger, Daniel Deon, Marc Gagnon, Kévin Saint-Jacques, Maximilian C. C. J. C. Ebert, Delphine Forge, Dominic Bastien, Damien Y. Colin, Jean Jacques Vanden Eynde, Anne Marinier, Albert M. Berghuis, Joelle N. Pelletier
Published 2019-06-01