HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope

by Daniela Fera, Matthew S. Lee, Kevin Wiehe, R. Ryan Meyerhoff, Alessandro Piai, Mattia Bonsignori, Baptiste Aussedat, William E. Walkowicz, Therese Ton, Jeffrey O. Zhou, Samuel Danishefsky, Barton F. Haynes, Stephen C. Harrison
Published 2018-03-01

Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans.

by Nelson R Wu, Nathan I Nicely, Esther M Lee, Rachel K Reed, Brian E Watts, Fangping Cai, William E Walkowicz, Baptiste Aussedat, Julia A Jones, Amanda Eaton, Ashley M Trama, S Munir Alam, David C Montefiori, Barton F Haynes, Kevin O Saunders
Published 2019-12-01

Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates.

by Joseph R Francica, Richard Laga, Geoffrey M Lynn, Gabriela Mužíková, Ladislav Androvič, Baptiste Aussedat, William E Walkowicz, Kartika Padhan, Ramiro Andrei Ramirez-Valdez, Robert Parks, Stephen D Schmidt, Barbara J Flynn, Yaroslav Tsybovsky, Guillaume B E Stewart-Jones, Kevin O Saunders, Faezzah Baharom, Constantinos Petrovas, Barton F Haynes, Robert A Seder
Published 2019-06-01

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates

by Kevin O. Saunders, Nathan I. Nicely, Kevin Wiehe, Mattia Bonsignori, R. Ryan Meyerhoff, Robert Parks, William E. Walkowicz, Baptiste Aussedat, Nelson R. Wu, Fangping Cai, Yusuf Vohra, Peter K. Park, Amanda Eaton, Eden P. Go, Laura L. Sutherland, Richard M. Scearce, Dan H. Barouch, Ruijun Zhang, Tarra Von Holle, R. Glenn Overman, Kara Anasti, Rogier W. Sanders, M. Anthony Moody, Thomas B. Kepler, Bette Korber, Heather Desaire, Sampa Santra, Norman L. Letvin, Gary J. Nabel, David C. Montefiori, Georgia D. Tomaras, Hua-Xin Liao, S. Munir Alam, Samuel J. Danishefsky, Barton F. Haynes
Published 2017-02-01