Mitochondrial Contribution to Parkinson's Disease Pathogenesis

by Anthony H. V. Schapira, Matthew Gegg
Published 2011-01-01

Exploring the Genotype–Phenotype Correlation in GBA-Parkinson Disease: Clinical Aspects, Biomarkers, and Potential Modifiers

by Elisa Menozzi, Anthony H. V. Schapira
Published 2021-06-01

Mitochondrial dysfunction associated with glucocerebrosidase deficiency

by Matthew E. Gegg, Anthony H.V. Schapira
Published 2016-06-01

Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells.

by Matthew E Gegg, J Mark Cooper, Anthony H V Schapira, Jan-Willem Taanman
Published 2009-01-01

A Human Neural Crest Stem Cell-Derived Dopaminergic Neuronal Model Recapitulates Biochemical Abnormalities in GBA1 Mutation Carriers

by Shi-Yu Yang, Michelle Beavan, Kai-Yin Chau, Jan-Willem Taanman, Anthony H.V. Schapira
Published 2017-03-01

L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils.

by Anna Migdalska-Richards, Michal Wegrzynowicz, Ian F Harrison, Guglielmo Verona, Vittorio Bellotti, Maria Grazia Spillantini, Anthony H V Schapira
Published 2020-01-01

A proposal for a comprehensive grading of Parkinson's disease severity combining motor and non-motor assessments: meeting an unmet need.

by Kallol Ray Chaudhuri, Jose Manuel Rojo, Anthony H V Schapira, David J Brooks, Fabrizio Stocchi, Per Odin, Angelo Antonini, Richard G Brown, Pablo Martinez-Martin
Published 2013-01-01

Correction: A Proposal for a Comprehensive Grading of Parkinson's Disease Severity Combining Motor and Non-Motor Assessments: Meeting an Unmet Need.

by Kallol Ray Chaudhuri, Jose Manuel Rojo, Anthony H V Schapira, David J Brooks, Fabrizio Stocchi, Per Odin, Angelo Antonini, Richard G Brown, Pablo Martinez-Martin
Published 2016-01-01

Ablation of the pro-inflammatory master regulator miR-155 does not mitigate neuroinflammation or neurodegeneration in a vertebrate model of Gaucher's disease

by Lisa Watson, Marcus Keatinge, Matthew Gegg, Qing Bai, M. Cosmin Sandulescu, Ayelet Vardi, Anthony H. Futerman, Anthony H.V. Schapira, Edward A. Burton, Oliver Bandmann
Published 2019-07-01

Resistance to the most common optic neuropathy is associated with systemic mitochondrial efficiency

by Gerassimos Lascaratos, Kai-Yin Chau, Haogang Zhu, Despoina Gkotsi, Rosalind King, Ivan Gout, Deborah Kamal, Philip J. Luthert, Anthony H.V. Schapira, David F. Garway-Heath
Published 2015-10-01

Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts.

by Anne Grünewald, Lisa Voges, Aleksandar Rakovic, Meike Kasten, Himesha Vandebona, Claudia Hemmelmann, Katja Lohmann, Slobodanka Orolicki, Alfredo Ramirez, Anthony H V Schapira, Peter P Pramstaller, Carolyn M Sue, Christine Klein
Published 2010-09-01

Investigation of somatic CNVs in brains of synucleinopathy cases using targeted SNCA analysis and single cell sequencing

by Diego Perez-Rodriguez, Maria Kalyva, Melissa Leija-Salazar, Tammaryn Lashley, Maxime Tarabichi, Viorica Chelban, Steve Gentleman, Lucia Schottlaender, Hannah Franklin, George Vasmatzis, Henry Houlden, Anthony H. V. Schapira, Thomas T. Warner, Janice L. Holton, Zane Jaunmuktane, Christos Proukakis
Published 2019-12-01

Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression

by Rubén Gómez-Sánchez, Matthew E. Gegg, José M. Bravo-San Pedro, Mireia Niso-Santano, Lydia Alvarez-Erviti, Elisa Pizarro-Estrella, Yolanda Gutiérrez-Martín, Alberto Alvarez-Barrientos, José M. Fuentes, Rosa Ana González-Polo, Anthony H.V. Schapira
Published 2014-02-01

Dopaminergic neuronal imaging in genetic Parkinson's disease: insights into pathogenesis.

by Alisdair McNeill, Ruey-Meei Wu, Kai-Yuan Tzen, Patricia C Aguiar, Jose M Arbelo, Paolo Barone, Kailash Bhatia, Orlando Barsottini, Vincenzo Bonifati, Sevasti Bostantjopoulou, Rodrigo Bressan, Giovanni Cossu, Pietro Cortelli, Andre Felicio, Henrique B Ferraz, Joanna Herrera, Henry Houlden, Marcelo Hoexter, Concepcion Isla, Andrew Lees, Oswaldo Lorenzo-Betancor, Niccolo E Mencacci, Pau Pastor, Sabina Pappata, Maria Teresa Pellecchia, Laura Silveria-Moriyama, Andrea Varrone, Tom Foltynie, Anthony H V Schapira
Published 2013-01-01

Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.

by Selina Wray, Matthew Self, NINDS Parkinson's Disease iPSC Consortium, NINDS Huntington's Disease iPSC Consortium, NINDS ALS iPSC Consortium, Patrick A Lewis, Jan-Willem Taanman, Natalie S Ryan, Colin J Mahoney, Yuying Liang, Michael J Devine, Una-Marie Sheerin, Henry Houlden, Huw R Morris, Daniel Healy, Jose-Felix Marti-Masso, Elisavet Preza, Suzanne Barker, Margaret Sutherland, Roderick A Corriveau, Michael D'Andrea, Anthony H V Schapira, Ryan J Uitti, Mark Guttman, Grzegorz Opala, Barbara Jasinska-Myga, Andreas Puschmann, Christer Nilsson, Alberto J Espay, Jaroslaw Slawek, Ludwig Gutmann, Bradley F Boeve, Kevin Boylan, A Jon Stoessl, Owen A Ross, Nicholas J Maragakis, Jay Van Gerpen, Melissa Gerstenhaber, Katrina Gwinn, Ted M Dawson, Ole Isacson, Karen S Marder, Lorraine N Clark, Serge E Przedborski, Steven Finkbeiner, Jeffrey D Rothstein, Zbigniew K Wszolek, Martin N Rossor, John Hardy
Published 2012-01-01