Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7.

by Leonie Unterholzner, Rebecca P Sumner, Marcin Baran, Hongwei Ren, Daniel S Mansur, Nollaig M Bourke, Felix Randow, Geoffrey L Smith, Andrew G Bowie
Published 2011-09-01

Alum Activates the Bovine NLRP3 Inflammasome

by Ciaran Harte, Ciaran Harte, Aoife L. Gorman, S. McCluskey, Michael Carty, Andrew G. Bowie, C. J. Scott, Kieran G. Meade, Ed C. Lavelle
Published 2017-11-01

Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence.

by Daniel S Mansur, Carlos Maluquer de Motes, Leonie Unterholzner, Rebecca P Sumner, Brian J Ferguson, Hongwei Ren, Pavla Strnadova, Andrew G Bowie, Geoffrey L Smith
Published 2013-02-01

IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

by Jessica F. Almine, Craig A. J. O’Hare, Gillian Dunphy, Ismar R. Haga, Rangeetha J. Naik, Abdelmadjid Atrih, Dympna J. Connolly, Jordan Taylor, Ian R. Kelsall, Andrew G. Bowie, Philippa M. Beard, Leonie Unterholzner
Published 2017-02-01

Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

by Xavier Sisquella, Yifat Ofir-Birin, Matthew A. Pimentel, Lesley Cheng, Paula Abou Karam, Natália G. Sampaio, Jocelyn Sietsma Penington, Dympna Connolly, Tal Giladi, Benjamin J. Scicluna, Robyn A. Sharples, Andreea Waltmann, Dror Avni, Eli Schwartz, Louis Schofield, Ziv Porat, Diana S. Hansen, Anthony T. Papenfuss, Emily M. Eriksson, Motti Gerlic, Andrew F. Hill, Andrew G. Bowie, Neta Regev-Rudzki
Published 2017-12-01

Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration

by Yifat Ofir-Birin, Hila Ben Ami Pilo, Abel Cruz Camacho, Ariel Rudik, Anna Rivkin, Or-Yam Revach, Netta Nir, Tal Block Tamin, Paula Abou Karam, Edo Kiper, Yoav Peleg, Reinat Nevo, Aryeh Solomon, Tal Havkin-Solomon, Alicia Rojas, Ron Rotkopf, Ziv Porat, Dror Avni, Eli Schwartz, Thomas Zillinger, Gunther Hartmann, Antonella Di Pizio, Neils Ben Quashie, Rivka Dikstein, Motti Gerlic, Ana Claudia Torrecilhas, Carmit Levy, Esther N. M. Nolte-‘t Hoen, Andrew G. Bowie, Neta Regev-Rudzki
Published 2021-08-01