Molecular Screening Strategy to Identify a Non-invasive Delivery Mechanism for the Treatment of Middle Ear Disorders

by Arwa Kurabi, Molly Cooper, Meghan Spriggs, Yuge Xu, Daniel Schaerer, Allen F. Ryan, Allen F. Ryan, Allen F. Ryan
Published 2020-12-01

Screening Mammalian Cochlear Hair Cells to Identify Critical Processes in Aminoglycoside-Mediated Damage

by Hyun Woo Lim, Hyun Woo Lim, Kwang Pak, Kwang Pak, Allen F. Ryan, Allen F. Ryan, Allen F. Ryan, Arwa Kurabi
Published 2018-07-01

An Antioxidant Screen Identifies Candidates for Protection of Cochlear Hair Cells from Gentamicin Toxicity

by Volker Noack, Kwang Pak, Kwang Pak, Rahul Jalota, Arwa Kurabi, Allen F. Ryan, Allen F. Ryan
Published 2017-08-01

Screening antioxidants for the protection of cochlear sensory cells

by Dong Gu Hur, Arwa Kurabi, Allen F Ryan
Published 2018-01-01

Lack of the hyaluronan receptor CD44 affects the course of bacterial otitis media and reduces leukocyte recruitment to the middle ear

by Hyun Woo Lim, Kwang Pak, Arwa Kurabi, Allen F. Ryan
Published 2019-06-01

A kinase inhibitor library screen identifies novel enzymes involved in ototoxic damage to the murine organ of Corti.

by Matthew Ryals, Kwang Pak, Rahul Jalota, Arwa Kurabi, Allen F Ryan
Published 2017-01-01

Peptides actively transported across the tympanic membrane: Functional and structural properties.

by Arwa Kurabi, Kerry A Beasley, Lisa Chang, James McCann, Kwang Pak, Allen F Ryan
Published 2017-01-01

A kinase inhibitor screen identifies signaling pathways regulating mucosal growth during otitis media.

by Julia Noel, Keigo Suzukawa, Eduardo Chavez, Kwang Pak, Stephen I Wasserman, Arwa Kurabi, Allen F Ryan
Published 2020-01-01

Ecrg4 attenuates the inflammatory proliferative response of mucosal epithelial cells to infection.

by Arwa Kurabi, Kwang Pak, Xitong Dang, Raul Coimbra, Brian P Eliceiri, Allen F Ryan, Andrew Baird
Published 2013-01-01

Single-Cell Transcriptomes Reveal a Complex Cellular Landscape in the Middle Ear and Differential Capacities for Acute Response to Infection

by Allen F. Ryan, Chanond A. Nasamran, Kwang Pak, Clara Draf, Kathleen M. Fisch, Nicholas Webster, Arwa Kurabi
Published 2020-04-01

A mouse model of otitis media identifies HB-EGF as a mediator of inflammation-induced mucosal proliferation.

by Keigo Suzukawa, Julia Tomlin, Kwang Pak, Eduardo Chavez, Arwa Kurabi, Andrew Baird, Stephen I Wasserman, Allen F Ryan
Published 2014-01-01

All Akt isoforms (Akt1, Akt2, Akt3) are involved in normal hearing, but only Akt2 and Akt3 are involved in auditory hair cell survival in the mammalian inner ear.

by Yves Brand, Soledad Levano, Vesna Radojevic, Arianne Monge Naldi, Cristian Setz, Allen F Ryan, Kwang Pak, Brian A Hemmings, Daniel Bodmer
Published 2015-01-01

NOD-Like Receptor Signaling in Cholesteatoma

by Anke Leichtle, Christin Klenke, Joerg Ebmeyer, Markus Daerr, Karl-Ludwig Bruchhage, Anna Sophie Hoffmann, Allen F. Ryan, Barbara Wollenberg, Holger Sudhoff
Published 2015-01-01

Extremes of age are associated with differences in the expression of selected pattern recognition receptor genes and ACE2, the receptor for SARS-CoV-2: implications for the epidemi...

by Stephen W. Bickler, David M. Cauvi, Kathleen M. Fisch, James M. Prieto, Alicia G. Sykes, Hariharan Thangarajah, David A. Lazar, Romeo C. Ignacio, Dale R. Gerstmann, Allen F. Ryan, Philip E. Bickler, Antonio De Maio
Published 2021-05-01