Liver Immune Microenvironment and Metastasis from Colorectal Cancer-Pathogenesis and Therapeutic Perspectives

by Xuezhen Zeng, Simon E. Ward, Jingying Zhou, Alfred S. L. Cheng
Published 2021-05-01

Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of telomerase (TERT) gene in hepatocellular carcinoma cells.

by Bin Zhang, Juan Chen, Alfred S L Cheng, Ben C B Ko
Published 2014-01-01

Epigenetic Activation of Wnt/β-Catenin Signaling in NAFLD-Associated Hepatocarcinogenesis

by Yuan Tian, Myth T.S. Mok, Pengyuan Yang, Alfred S.L. Cheng
Published 2016-08-01

The TEAD Family and Its Oncogenic Role in Promoting Tumorigenesis

by Yuhang Zhou, Tingting Huang, Alfred S. L. Cheng, Jun Yu, Wei Kang, Ka Fai To
Published 2016-01-01

The physiological role of Motin family and its dysregulation in tumorigenesis

by Tingting Huang, Yuhang Zhou, Jinglin Zhang, Alfred S. L. Cheng, Jun Yu, Ka Fai To, Wei Kang
Published 2018-04-01

The Interplay of LncRNA-H19 and Its Binding Partners in Physiological Process and Gastric Carcinogenesis

by Li Zhang, Yuhang Zhou, Tingting Huang, Alfred S. L. Cheng, Jun Yu, Wei Kang, Ka Fai To
Published 2017-02-01

Targeting the Oncogenic FGF-FGFR Axis in Gastric Carcinogenesis

by Jinglin Zhang, Patrick M. K. Tang, Yuhang Zhou, Alfred S. L. Cheng, Jun Yu, Wei Kang, Ka Fai To
Published 2019-06-01

Mechanotransduction and Cytoskeleton Remodeling Shaping YAP1 in Gastric Tumorigenesis

by Jinglin Zhang, Yuhang Zhou, Patrick M.K. Tang, Alfred S.L. Cheng, Jun Yu, Ka Fai To, Wei Kang
Published 2019-03-01

Hydrogen sulfide lowers proliferation and induces protective autophagy in colon epithelial cells.

by Ya C Wu, Xiao J Wang, Le Yu, Francis K L Chan, Alfred S L Cheng, Jun Yu, Joseph J Y Sung, William K K Wu, Chi H Cho
Published 2012-01-01

Androgen receptor drives hepatocellular carcinogenesis by activating enhancer of zeste homolog 2-mediated Wnt/β-catenin signalingResearch in context

by Haibin Song, Zhuo Yu, Xuehua Sun, Jun Feng, Qi Yu, Hanif Khan, Xiaojun Zhu, Lingying Huang, Man Li, Myth T.S. Mok, Alfred S.L. Cheng, Yueqiu Gao, Hai Feng
Published 2018-09-01

IGF2BP3 functions as a potential oncogene and is a crucial target of miR-34a in gastric carcinogenesis

by Yuhang Zhou, Tingting Huang, Ho Lam Siu, Chi Chun Wong, Yujuan Dong, Feng Wu, Bin Zhang, William K. K. Wu, Alfred S. L. Cheng, Jun Yu, Ka Fai To, Wei Kang
Published 2017-04-01

Stathmin1 plays oncogenic role and is a target of microRNA-223 in gastric cancer.

by Wei Kang, Joanna H M Tong, Anthony W H Chan, Raymond W M Lung, Shuk Ling Chau, Queenie W L Wong, Nathalie Wong, Jun Yu, Alfred S L Cheng, Ka Fai To
Published 2012-01-01

Aberrant Transforming Growth Factor β1 Signaling and SMAD4 Nuclear Translocation Confer Epigenetic Repression of ADAM19 in Ovarian Cancer

by Michael W.Y. Chan, Yi-Wen Huang, Corinna Hartman-Frey, Chieh-Ti Kuo, Daniel Deatherage, Huaxia Qin, Alfred S.L. Cheng, Pearlly S. Yan, Ramana V. Davuluri, Tim H.-M. Huang, Kenneth P. Nephew, Huey-Jen L. Lin
Published 2008-09-01

Correction: FK-16 Derived from the Anticancer Peptide LL-37 Induces Caspase-Independent Apoptosis and Autophagic Cell Death in Colon Cancer Cells.

by Shun X Ren, Jin Shen, Alfred S L Cheng, Lan Lu, Ruby L Y Chan, Zhi J Li, Xiao J Wang, Clover C M Wong, Lin Zhang, Simon S M Ng, Franky L Chan, Francis K L Chan, Jun Yu, Joseph J Y Sung, William K K Wu, Chi H Cho
Published 2015-01-01

FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells.

by Shun X Ren, Jin Shen, Alfred S L Cheng, Lan Lu, Ruby L Y Chan, Zhi J Li, Xiao J Wang, Clover C M Wong, Lin Zhang, Simon S M Ng, Franky L Chan, Francis K L Chan, Jun Yu, Joseph J Y Sung, William K K Wu, Chi H Cho
Published 2013-01-01

ER-residential Nogo-B accelerates NAFLD-associated HCC mediated by metabolic reprogramming of oxLDL lipophagy

by Yuan Tian, Bin Yang, Weinan Qiu, Yajing Hao, Zhenxing Zhang, Bo Yang, Nan Li, Shuqun Cheng, Zhangjun Lin, Yao-cheng Rui, Otto K. W. Cheung, Weiqin Yang, William K. K. Wu, Yue-Sun Cheung, Paul B. S. Lai, Jianjun Luo, Joseph J. Y. Sung, Runsheng Chen, Hong-Yang Wang, Alfred S. L. Cheng, Pengyuan Yang
Published 2019-07-01

An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma

by Hanyong Sun, Weiqin Yang, Yuan Tian, Xuezhen Zeng, Jingying Zhou, Myth T. S. Mok, Wenshu Tang, Yu Feng, Liangliang Xu, Anthony W. H. Chan, Joanna H. Tong, Yue-Sun Cheung, Paul B. S. Lai, Hector K. S. Wang, Shun-Wa Tsang, King-Lau Chow, Mengying Hu, Rihe Liu, Leaf Huang, Bing Yang, Pengyuan Yang, Ka-Fai To, Joseph J. Y. Sung, Grace L. H. Wong, Vincent W. S. Wong, Alfred S. L. Cheng
Published 2018-12-01

The Intersection between Oral Microbiota, Host Gene Methylation and Patient Outcomes in Head and Neck Squamous Cell Carcinoma

by Zigui Chen, Po Yee Wong, Cherrie W. K. Ng, Linlin Lan, Sherwood Fung, Jing W. Li, Liuyang Cai, Pu Lei, Qianqian Mou, Sunny H. Wong, William K. K. Wu, Ryan J. Li, Katie Meehan, Vivian W. Y. Lui, Chit Chow, Kwok W. Lo, Amy B. W. Chan, Siaw Shi Boon, Eric H. L. Lau, Zenon Yeung, Kwan C. Allen Chan, Eddy W. Y. Wong, Alfred S. L. Cheng, Jun Yu, Paul K. S. Chan, Jason Y. K. Chan
Published 2020-11-01