A consensus set of genetic vulnerabilities to ATR inhibition

by Nicole Hustedt, Alejandro Álvarez-Quilón, Andrea McEwan, Jing Yi Yuan, Tiffany Cho, Lisa Koob, Traver Hart, Daniel Durocher
Published 2019-09-01

Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks

by Pierre Caron, Jonathan Choudjaye, Thomas Clouaire, Béatrix Bugler, Virginie Daburon, Marion Aguirrebengoa, Thomas Mangeat, Jason S. Iacovoni, Alejandro Álvarez-Quilón, Felipe Cortés-Ledesma, Gaëlle Legube
Published 2015-11-01

TDP2-dependent non-homologous end-joining protects against topoisomerase II-induced DNA breaks and genome instability in cells and in vivo.

by Fernando Gómez-Herreros, Rocío Romero-Granados, Zhihong Zeng, Alejandro Alvarez-Quilón, Cristina Quintero, Limei Ju, Lieve Umans, Liesbeth Vermeire, Danny Huylebroeck, Keith W Caldecott, Felipe Cortés-Ledesma
Published 2013-01-01

Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency

by Alejandro Álvarez-Quilón, José Terrón-Bautista, Irene Delgado-Sainz, Almudena Serrano-Benítez, Rocío Romero-Granados, Pedro Manuel Martínez-García, Silvia Jimeno-González, Cristina Bernal-Lozano, Cristina Quintero, Lourdes García-Quintanilla, Felipe Cortés-Ledesma
Published 2020-02-01