Immune Condition of Colorectal Cancer Patients Featured by Serum Chemokines and Gene Expressions of CD4+ Cells in Blood

by Takuya Komura, Masaaki Yano, Akimitsu Miyake, Hisashi Takabatake, Masaki Miyazawa, Norihiko Ogawa, Akihiro Seki, Masao Honda, Takashi Wada, Shigeyuki Matsui, Shuichi Kaneko, Yoshio Sakai
Published 2018-01-01

Gut-derived Enterococcus faecium from ulcerative colitis patients promotes colitis in a genetically susceptible mouse host

by Jun Seishima, Noriho Iida, Kazuya Kitamura, Masahiro Yutani, Ziyu Wang, Akihiro Seki, Taro Yamashita, Yoshio Sakai, Masao Honda, Tatsuya Yamashita, Takashi Kagaya, Yukihiro Shirota, Yukako Fujinaga, Eishiro Mizukoshi, Shuichi Kaneko
Published 2019-11-01

Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice

by Kosuke Ishida, Akihiro Seki, Kazunori Kawaguchi, Alessandro Nasti, Masatoshi Yamato, Hiiro Inui, Takuya Komura, Taro Yamashita, Kuniaki Arai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Takashi Wada, Kenichi Harada, Shuichi Kaneko, Yoshio Sakai
Published 2021-07-01

LECT2 as a hepatokine links liver steatosis to inflammation via activating tissue macrophages in NASH

by Noboru Takata, Kiyo-aki Ishii, Hiroaki Takayama, Mayumi Nagashimada, Kyoko Kamoshita, Takeo Tanaka, Akihiro Kikuchi, Yumie Takeshita, Yukako Matsumoto, Tsuguhito Ota, Yasuhiko Yamamoto, Satoshi Yamagoe, Akihiro Seki, Yoshio Sakai, Shuichi Kaneko, Toshinari Takamura
Published 2021-01-01

Phase I clinical study of liver regenerative therapy for cirrhosis by intrahepatic arterial infusion of freshly isolated autologous adipose tissue-derived stromal/stem (regenerativ...

by Yoshio Sakai, Masayuki Takamura, Akihiro Seki, Hajime Sunagozaka, Takeshi Terashima, Takuya Komura, Masatoshi Yamato, Masaki Miyazawa, Kazunori Kawaguchi, Alessandro Nasti, Hatsune Mochida, Soichiro Usui, Nobuhisa Otani, Takahiro Ochiya, Takashi Wada, Masao Honda, Shuichi Kaneko
Published 2017-06-01

BMP9‐ID1 signaling promotes EpCAM‐positive cancer stem cell properties in hepatocellular carcinoma

by Han Chen, Kouki Nio, Taro Yamashita, Hikari Okada, Ru Li, Tsuyoshi Suda, Yingyi Li, Phuong Thi Bich Doan, Akihiro Seki, Hidetoshi Nakagawa, Tadashi Toyama, Takeshi Terashima, Noriho Iida, Tetsuro Shimakami, Hajime Takatori, Kazunori Kawaguchi, Yoshio Sakai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Shuichi Kaneko
Published 2021-08-01

Clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for exploration of its safety and efficacy

by Yoshio Sakai, Shinya Fukunishi, Masayuki Takamura, Kazunori Kawaguchi, Oto Inoue, Soichiro Usui, Shinichiro Takashima, Akihiro Seki, Akira Asai, Yusuke Tsuchimoto, Alessandro Nasti, Tuyen Thuy Bich Ho, Yasuhito Imai, Kenichi Yoshimura, Toshinori Murayama, Taro Yamashita, Kuniaki Arai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Takashi Wada, Kenichi Harada, Kazuhide Higuchi, Shuichi Kaneko
Published 2021-12-01