The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner.

by Jieru Meng, Mourad Majidi, Bingliang Fang, Lin Ji, B Nebiyou Bekele, John D Minna, Jack A Roth
Published 2013-01-01

Mesenchymal Stem Cells Display Tumor-Specific Tropism in an RCAS/Ntv-a Glioma Model

by Tiffany Doucette, Ganesh Rao, Yuhui Yang, Joy Gumin, Naoki Shinojima, B. Nebiyou Bekele, Wei Qiao, Wei Zhang, Frederick F. Lang
Published 2011-08-01

Comparative Effect of Oncolytic Adenoviruses with E1 A or E113-55 kDa Deletions in Malignant Gliomas

by Hong Jiang, Candelaria Gomez-Manzano, Ramon Alemany, Diana Medrano, Marta Alonso, B. Nebiyou Bekele, E Lin, Charles C. Conrad, W.K. Alfred Yung, Juan Fueyo
Published 2005-01-01

Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo.

by Jieru Meng, Bingbing Dai, Bingliang Fang, B Nebiyou Bekele, William G Bornmann, Duoli Sun, Zhenghong Peng, Roy S Herbst, Vassiliki Papadimitrakopoulou, John D Minna, Michael Peyton, Jack A Roth
Published 2010-11-01

Sustained Angiopoietin-2 Expression Disrupts Vessel Formation and Inhibits Glioma Growth

by Ok-Hee Lee, Juan Fueyo, Jing Xu, W.K. Alfred Yung, Michael G. Lemoine, Frederick F. Lang, B. Nebiyou Bekele, Xian Zhou, Marta A. Alonso, Kenneth D. Aldape, Gregory N. Fuller, Candelaria Gomez-Manzano
Published 2006-05-01

Exogenous Restoration of TUSC2 Expression Induces Responsiveness to Erlotinib in Wildtype Epidermal Growth Factor Receptor (EGFR) Lung Cancer Cells through Context Specific Pathway...

by Bingbing Dai, Shaoyu Yan, Humberto Lara-Guerra, Hiroyuki Kawashima, Ryo Sakai, Gitanjali Jayachandran, Mourad Majidi, Reza Mehran, Jing Wang, B Nebiyou Bekele, Veerabhadran Baladandayuthapani, Suk-Young Yoo, Ying Wang, Jun Ying, Feng Meng, Lin Ji, Jack A Roth
Published 2015-01-01