Standardized and reproducible measurement of decision-making in mice

by The International Brain Laboratory, Valeria Aguillon-Rodriguez, Dora Angelaki, Hannah Bayer, Niccolo Bonacchi, Matteo Carandini, Fanny Cazettes, Gaelle Chapuis, Anne K Churchland, Yang Dan, Eric Dewitt, Mayo Faulkner, Hamish Forrest, Laura Haetzel, Michael Häusser, Sonja B Hofer, Fei Hu, Anup Khanal, Christopher Krasniak, Ines Laranjeira, Zachary F Mainen, Guido Meijer, Nathaniel J Miska, Thomas D Mrsic-Flogel, Masayoshi Murakami, Jean-Paul Noel, Alejandro Pan-Vazquez, Cyrille Rossant, Joshua Sanders, Karolina Socha, Rebecca Terry, Anne E Urai, Hernando Vergara, Miles Wells, Christian J Wilson, Ilana B Witten, Lauren E Wool, Anthony M Zador
Published 2021-05-01

TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex

by Nicole Merritt, Keith Garcia, Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas
Published 2021-04-01

Development and validation of a nomogram to better predict hypertension based on a 10-year retrospective cohort study in China

by Xinna Deng, Huiqing Hou, Xiaoxi Wang, Qingxia Li, Xiuyuan Li, Zhaohua Yang, Haijiang Wu
Published 2021-05-01

Recovery of consciousness and cognition after general anesthesia in humans

by George A Mashour, Ben JA Palanca, Mathias Basner, Duan Li, Wei Wang, Stefanie Blain-Moraes, Nan Lin, Kaitlyn Maier, Maxwell Muench, Vijay Tarnal, Giancarlo Vanini, E Andrew Ochroch, Rosemary Hogg, Marlon Schwartz, Hannah Maybrier, Randall Hardie, Ellen Janke, Goodarz Golmirzaie, Paul Picton, Andrew R McKinstry-Wu, Michael S Avidan, Max B Kelz
Published 2021-05-01

A novel ATP dependent dimethylsulfoniopropionate lyase in bacteria that releases dimethyl sulfide and acryloyl-CoA

by Chun-Yang Li, Xiu-Juan Wang, Xiu-Lan Chen, Qi Sheng, Shan Zhang, Peng Wang, Mussa Quareshy, Branko Rihtman, Xuan Shao, Chao Gao, Fuchuan Li, Shengying Li, Weipeng Zhang, Xiao-Hua Zhang, Gui-Peng Yang, Jonathan D Todd, Yin Chen, Yu-Zhong Zhang
Published 2021-05-01

Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels

by Briana J Martiszus, Timur Tsintsadze, Wenhan Chang, Stephen M Smith
Published 2021-05-01

The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains

by Alan Rodriguez Carvajal, Irina Grishkovskaya, Carlos Gomez Diaz, Antonia Vogel, Adar Sonn-Segev, Manish S Kushwah, Katrin Schodl, Luiza Deszcz, Zsuzsanna Orban-Nemeth, Shinji Sakamoto, Karl Mechtler, Philipp Kukura, Tim Clausen, David Haselbach, Fumiyo Ikeda
Published 2021-06-01

The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia

by Katalin Skrapits, Miklós Sárvári, Imre Farkas, Balázs Göcz, Szabolcs Takács, Éva Rumpler, Viktória Váczi, Csaba Vastagh, Gergely Rácz, András Matolcsy, Norbert Solymosi, Szilárd Póliska, Blanka Tóth, Ferenc Erdélyi, Gábor Szabó, Michael D Culler, Cecile Allet, Ludovica Cotellessa, Vincent Prévot, Paolo Giacobini, Erik Hrabovszky
Published 2021-06-01

Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

by Seungjin Ryu, Irina Shchukina, Yun-Hee Youm, Hua Qing, Brandon Hilliard, Tamara Dlugos, Xinbo Zhang, Yuki Yasumoto, Carmen J Booth, Carlos Fernández-Hernando, Yajaira Suárez, Kamal Khanna, Tamas L Horvath, Marcelo O Dietrich, Maxim Artyomov, Andrew Wang, Vishwa Deep Dixit
Published 2021-06-01

The human cerebellum is essential for modulating perceptual sensitivity based on temporal expectations

by Assaf Breska, Richard B Ivry
Published 2021-06-01

Nanoscape, a data-driven 3D real-time interactive virtual cell environment

by Shereen R Kadir, Andrew Lilja, Nick Gunn, Campbell Strong, Rowan T Hughes, Benjamin J Bailey, James Rae, Robert G Parton, John McGhee
Published 2021-06-01

The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy

by Yang Guo, Ze-Yan Yu, Jianxin Wu, Hutao Gong, Scott Kesteven, Siiri E Iismaa, Andrea Y Chan, Sara Holman, Silvia Pinto, Andy Pironet, Charles D Cox, Robert M Graham, Rudi Vennekens, Michael P Feneley, Boris Martinac
Published 2021-06-01

Contribution of dorsal horn CGRP-expressing interneurons to mechanical sensitivity

by Line S Löken, Joao M Braz, Alexander Etlin, Mahsa Sadeghi, Mollie Bernstein, Madison Jewell, Marilyn Steyert, Julia Kuhn, Katherine Hamel, Ida J Llewellyn-Smith, Allan Basbaum
Published 2021-06-01

Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations

by Wenqing Li, Virginia Tran, Iftach Shaked, Belinda Xue, Thomas Moore, Rhonda Lightle, David Kleinfeld, Issam A Awad, Mark H Ginsberg
Published 2021-05-01

Watching hair turn grey

by Michael P Philpott
Published 2021-06-01

RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis

by Máté Nászai, Karen Bellec, Yachuan Yu, Alvaro Román-Fernández, Emma Sandilands, Joel Johansson, Andrew D Campbell, Jim C Norman, Owen J Sansom, David M Bryant, Julia B Cordero
Published 2021-06-01

SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B

by Wei Fan, Shuang Tang, Xiaojuan Fan, Yi Fang, Xiaojiang Xu, Leping Li, Jian Xu, Jian-Liang Li, Zefeng Wang, Xiaoling Li
Published 2021-05-01

Cortical signatures of precision grip force control in children, adolescents, and adults

by Mikkel Malling Beck, Meaghan Elizabeth Spedden, Martin Jensen Dietz, Anke Ninija Karabanov, Mark Schram Christensen, Jesper Lundbye-Jensen
Published 2021-06-01

Allosteric conformational ensembles have unlimited capacity for integrating information

by John W Biddle, Rosa Martinez-Corral, Felix Wong, Jeremy Gunawardena
Published 2021-06-01

Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta

by Matthew William Grol, Nele A Haelterman, Joohyun Lim, Elda M Munivez, Marilyn Archer, David M Hudson, Sara F Tufa, Douglas R Keene, Kevin Lei, Dongsu Park, Cole D Kuzawa, Catherine G Ambrose, David R Eyre, Brendan H Lee
Published 2021-05-01