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283by Mayara Garcia de Mattos Barbosa, Hui Liu, Daniel Huynh, Greg Shelley, Evan T. Keller, Brian T. Emmer, Emily Sherman, David Ginsburg, Andrew A. Kennedy, Andrew W. Tai, Christiane Wobus, Carmen Mirabeli, Thomas M. Lanigan, Milagros Samaniego, Wenzhao Meng, Aaron M. Rosenfeld, Eline T. Luning Prak, Jeffrey L. Platt, Marilia Cascalho“... that potency of neutralization was acquired by somatic hypermutation and selection of B cells. These results...”
Published 2021-05-01
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284by Bishnudeo Roy, Anne-Margarete Brennecke, Shiwani Agarwal, Martina Krey, Sandra Düber, Siegfried Weiss“... cells. Additionally, high frequency of nucleotide exchanges indicating somatic hypermutation in VH...”
Published 2013-01-01
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285Aging induces B cell defects and decreased antibody responses to influenza infection and vaccination“... somatic hypermutation of the antibody variable region, 3) reduced binding and neutralization capacity...”
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286“... and ADAR deaminases that are known to be involved in normal locus-specific immunoglobulin somatic...”
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287by Long Ma, Xiaomei Wang, Xiaoying Bi, Jiezuan Yang, Bin Shi, Xiaoyan He, Rui Ma, Qingqing Ma, Xinsheng Yao“... that the mechanism of high frequency CDR3 generation might be associated with the maturation of IgG affinity (somatic...”
Published 2017-01-01
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288“..., and aberrant somatic hypermutation of protooncogenes. The occurrence of IGV mutations in the overwhelming...”
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289by Daniela Frasca, Alain Diaz, Maria Romero, Thomas Vazquez, Natasa Strbo, Laura Romero, Ryan M. McCormack, Eckhard R. Podack, Bonnie B. Blomberg“... of activation-induced cytidine deaminase (AID), the enzyme for class switch recombination, somatic hypermutation...”
Published 2020-02-01
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290by Qingchen Zhang, Lu Zhang, Chen Zhou, Yiyan Yang, Zuojing Yin, Dingfeng Wu, Kailin Tang, Zhiwei Cao“... and then diversified by somatic hypermutation. Identifying the combination of sourcing germline genes is critical...”
Published 2019-03-01
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291by Hiroaki Kaku, Nichol E. Holodick, Joseph R. Tumang, Thomas L. Rothstein, Thomas L. Rothstein, Thomas L. Rothstein“... deaminase (AID), a product of the Aicda gene, plays a central role in class-switch recombination and somatic...”
Published 2017-06-01
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292by Chaohui Yuan, Charles C Chu, Xiao-Jie Yan, Davide Bagnara, Nicholas Chiorazzi, Thomas MacCarthy“... of mutability derived from somatic hypermutation data. Furthermore, this correlation is not observed...”
Published 2017-01-01
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293by Esther M. Vletter, Esther M. Vletter, Marvyn T. Koning, Hans Ulrich Scherer, Hendrik Veelken, Rene E. M. Toes“... result of the presence of N-linked glycosylation that most often have been introduced by somatic...”
Published 2020-02-01
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294“...The role of Activation-Induced Cytidine Deaminase (AID) in somatic hypermutation and polyclonal...”
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295by Marjon Navis, Karen Tran, Shridhar Bale, Ganesh E Phad, Javier Guenaga, Richard Wilson, Martina Soldemo, Krisha McKee, Christopher Sundling, John Mascola, Yuxing Li, Richard T Wyatt, Gunilla B Karlsson Hedestam“... predominantly through the HCDR2. Also unlike VRC01, GE356 was minimally modified by somatic hypermutation, its...”
Published 2014-08-01
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296by Alireza G. Senejani, Yanfeng Liu, Dawit Kidane, Stephen E. Maher, Caroline J. Zeiss, Hong-Jae Park, Michael Kashgarian, Jennifer M. McNiff, Daniel Zelterman, Alfred L.M. Bothwell, Joann B. Sweasy“...-chain junctions and somatic hypermutation is dramatically increased. These results demonstrate...”
Published 2014-01-01
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297by Barton F. Haynes, Dimiter S. Dimitrov, Huaxin Liao, Gerald V. Quinnan, Christopher C. Broder, Zhongyu Zhu, Weizao Chen“... (IgGs) and highly somatically hypermutated which could impede their elicitation. Ig Ms (IgMs...”
Published 2010-02-01
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298by Ben S. Wendel, Chenfeng He, Peter D. Crompton, Susan K. Pierce, Ning Jiang, Ning Jiang“... novel germline alleles. Somatic hypermutation (SHM) calling requires a reference germline sequence...”
Published 2017-09-01
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299“...) and somatic hypermutation (SHM), as well as differentiation to memory B cells or long-lived plasma cells...”
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300“... hypermethylation, and aberrant somatic hypermutation of protooncogenes. The occurrence of IGV mutations...”
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