Genotoxic Pyrrolizidine Alkaloids — Mechanisms Leading to DNA Adduct Formation and Tumorigenicity

by Ming W. Chou, Ge Lin, Qingsu Xia, Peter P. Fu
Published 2002-09-01

Occurrence and Risk Assessment of Pyrrolizidine Alkaloids in Spices and Culinary Herbs from Various Geographical Origins

by Florian Kaltner, Michael Rychlik, Manfred Gareis, Christoph Gottschalk
Published 2020-03-01

Interactions between Plant Metabolites Affect Herbivores: A Study with Pyrrolizidine Alkaloids and Chlorogenic Acid

by Xiaojie Liu, Klaas Vrieling, Peter G.L. Klinkhamer
Published 2017-05-01

Bacterial 16S ribosomal DNA analysis of pyrrolizidine alkaloid detoxifying enrichments from the ovine rumen

by Gray, Diane R.
Published 2012

Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats

by Fuscoe James C, Liu Ruqing, Guo Lei, Mei Nan, Chen Tao
Published 2007-11-01

Low pyrrolizidine alkaloid levels in perennial ryegrass is associated with the absence of a homospermidine synthase gene

by Geoffrey P. Gill, Catherine J. Bryant, Mikhail Fokin, Jan Huege, Karl Fraser, Chris Jones, Mingshu Cao, Marty J. Faville
Published 2018-04-01

7-N-Acetylcysteine-pyrrole conjugate—A potent DNA reactive metabolite of pyrrolizidine alkaloids

by Xiaobo He, Liang Ma, Qingsu Xia, Peter P. Fu
Published 2016-10-01

Pyrrolizidine Alkaloids Induce Cell Death in Human HepaRG Cells in a Structure-Dependent Manner

by Josephin Glück, Julia Waizenegger, Albert Braeuning, Stefanie Hessel-Pras
Published 2021-12-01

Quercetin prevents pyrrolizidine alkaloid clivorine-induced liver injury in mice by elevating body defense capacity.

by Lili Ji, Yibo Ma, Zaiyong Wang, Zhunxiu Cai, Chun Pang, Zhengtao Wang
Published 2014-01-01

The determination of the partition coefficients for a variety of pyrrolizidine alkaloids...

by Ryan, Edward Thomas
Published 2009

Independent recruitment of a flavin-dependent monooxygenase for safe accumulation of sequestered pyrrolizidine alkaloids in grasshoppers and moths.

by Linzhu Wang, Till Beuerle, James Timbilla, Dietrich Ober
Published 2012-01-01

Risks for human health related to the presence of pyrrolizidine alkaloids in honey, tea, herbal infusions and food supplements

by EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Lutz Edler, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P. Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, José Angel Gomez Ruiz, Marco Binaglia
Published 2017-07-01

Case Report. The first report of pyrrolizidine alkaloid poisoning in a gazelle (Gazella Subgutturosa) – histopathologic diagnosis

by Khordadmehr Monireh, Rezazadeh Fereydoon, Ashrafi-Helan Javad, Hosseini-Ghomi Mir Mohsen
Published 2016-03-01

GENOTOXICITY OF THE PYRROLIZIDINE ALKALOIDS: ASSOCIATION WITH ADVERSE HEPATIC EFFECTS (ALKALINE ELUTION, CHEMICAL CARCINOGENESIS, ANTIMITOTIC EFFECTS).

by PETRY, THOMAS WILLIAM.
Published 1984

Opinion of the Panel on contaminants in the food chain [CONTAM] related to pyrrolizidine alkaloids as undesirable substances in animal feed

by European Food Safety Authority (EFSA)
Published 2007-05-01

Heliotropium; a genus rich in pyrrolizidine alkaloids: A systematic review following its phytochemistry and pharmacology

by Marwa A.A. Fayed
Published 2021-05-01

Analysis of pyrrolizidine alkaloids in Crotalaria species by HPLC-MS/MS in order to evaluate related food health risks

by Rosemann, G.M. (Gertruida Magdalena)
Published 2013

Simultaneous Determination and Risk Assessment of Pyrrolizidine Alkaloids in Artemisia capillaris Thunb. by UPLC-MS/MS Together with Chemometrics

by Li-Hua Chen, Jun-Chi Wang, Qi-Lei Guo, Yue Qiao, Hui-Juan Wang, Yong-Hong Liao, Di-An Sun, Jian-Yong Si
Published 2019-03-01

An Outbreak of Hepatic Veno-Occlusive Disease in Western Afghanistan Associated with Exposure to Wheat Flour Contaminated with Pyrrolizidine Alkaloids

by Faizullah Kakar, Zarif Akbarian, Toby Leslie, Mir Lais Mustafa, John Watson, Hans P. van Egmond, Mohammad Fahim Omar, Jawad Mofleh
Published 2010-01-01

Quantitation of DNA reactive pyrrolic metabolites of senecionine – A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis

by Qingsu Xia, Xiaobo He, Qiang Shi, Ge Lin, Peter P. Fu
Published 2020-01-01