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  1. 141
    Development of carbamate modified PEI for delivery of a granzyme B inhibitor gene to protect against cytotoxic lymphocyte killing
    by Cheng, Wei
    Published 2013
    “... infected or transformed cells using granzyme B (GrB) to induce apoptosis. However, GrB-induced apoptosis...”
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  2. 142
    Enteric bacteria induce IFNγ and Granzyme B from human colonic Group 1 Innate Lymphoid Cells
    “... induced significant expression of Granzyme B in NK cells and ILC1s. Overall, these data demonstrate...”
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    Article
  3. 143
    Toward a molecular understanding of adaptive immunity: A chronology, part III.
    by Kendall A Smith
    Published 2014-02-01
    Subjects: “...Granzymes...”
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    Article
  4. 144
    Dynamic conformations of nucleophosmin (NPM1) at a key monomer-monomer interface affect oligomer stability and interactions with granzyme B.
    “... tissue formed an unusually stable oligomer and showed increased susceptibility to cleavage by granzyme B...”
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    Article
  5. 145
    Design and synthesis of putative inhibitors of Granzyme B and Liver Receptor Homolog-1, and, Increasing the bioavailability of Fulvestrant in the treatment of breast cancer
    by Buisson, Lauriane
    Published 2014
    “... inhibitors of various targets involved in cancer development. Granzyme B (Grb) inhibitors: GrB...”
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  6. 146
    Axons are injured by antigen-specific CD8+ T cells through a MHC class I- and granzyme B-dependent mechanism
    “... presentation, T cell receptor specificity and axoplasmic granzyme B activity. Despite extensive distal CTL...”
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    Article
  7. 147
    Circulating mature granzyme B+ T cells distinguish Crohn’s disease-associated axial spondyloarthritis from axial spondyloarthritis and Crohn’s disease
    “... significant increase in granzyme B+ T cells of both CD4+ and CD8+ lineages by both scRNAseq and flow cytometry...”
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    Article
  8. 148
    Cloning CTL-Specific Genes (and now for something completely differential)
    by R Chris Bleackley
    Published 2014-10-01
    Subjects: “...Granzymes...”
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    Article
  9. 149
    Implication de la protéine suppresseur de tumeurs p53 dans la mort cellulaire induite par les lymphocytes T cytotoxiques et les cellules NK : rôle dans la régulation de l’apoptose dépendante du granzyme B
    by Ben Safta, Thouraya
    Published 2017
    Subjects: “...Granzyme B...”
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  10. 150
    Dissociated expression of granzyme B and IFN-gamma by T lymphocytes in HIV-1 infected individuals and its implications for Tc1 effector diversity
    by Kleen, Thomas Oliver
    Published 2003
    “... extent these two effector function of CD8+ cells are linked. Granzyme B (GzB) is stored in cytolytic...”
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    Doctoral Thesis
  11. 151
    Granzyme B is correlated with clinical outcome after PD-1 blockade in patients with stage IV non-small-cell lung cancer
    “... granzyme B, as well as germline variation of the GZMB gene, with clinical outcome to programmed cell death...”
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    Article
  12. 152
    Maltose-binding protein enhances secretion of recombinant human granzyme B accompanied by in vivo processing of a precursor MBP fusion protein.
    “...<h4>Background</h4>The apoptosis-inducing serine protease granzyme B (GrB) is an important factor...”
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    Article
  13. 153
    Genetic variants of human granzyme B predict transplant outcomes after HLA matched unrelated bone marrow transplantation for myeloid malignancies.
    “...Serine protease granzyme B plays important roles in infections, autoimmunity, transplant rejection...”
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    Article
  14. 154
    Type I interferon suppresses tumor growth through activating the STAT3-granzyme B pathway in tumor-infiltrating cytotoxic T lymphocytes
    Subjects: “...Granzyme B...”
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    Article
  15. 155
    Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes.
    “..., differentiation into cytotoxic effector cells, and release of granzyme B (GrB), a key effector of CD8+ T cell...”
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    Article
  16. 156
    Single-Fluorescent Protein Reporters Allow Parallel Quantification of Natural Killer Cell-Mediated Granzyme and Caspase Activities in Single Target Cells
    Subjects: “...granzyme and caspase activity...”
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    Article
  17. 157
    Combination of prodrugs perforin-CEBPD and perforin-granzyme B enhance a stronger activation of caspase signaling in efficiently killing prostate cancer
    by Yun-HsuanChou, 周昀璇
    Published 2012
    “... (induction of procaspase 8 level) and granzyme B prodrug (an activator of procaspase 8) could trigger...”
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    Others
  18. 158
    Primary Tr1 cells from metastatic melanoma eliminate tumor-promoting macrophages through granzyme B- and perforin-dependent mechanisms
    “... in melanomas, and suppressing antitumor immunity. Because granzyme B- and perforin-expressing Tr1 cells could...”
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    Article
  19. 159
    Natural Killer Cell Phenotype and Functionality Affected by Exposure to Extracellular Survivin and Lymphoma-Derived Exosomes
    Subjects: “...granzyme...”
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    Article
  20. 160
    Correction: Therapeutic efficacy and safety of a human fusion construct targeting the TWEAK receptor Fn14 and containing a modified granzyme B
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    Article
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