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641by Aya Kurosawa, Shinta Saito, Sairei So, Mitsumasa Hashimoto, Kuniyoshi Iwabuchi, Haruka Watabe, Noritaka Adachi“... demonstrate that Artemis-null human cells display increased gene-targeting efficiencies, particularly...”
Published 2013-01-01
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642by Rafael Nisa-Martínez, Philippe Laporte, José Ignacio Jiménez-Zurdo, Florian Frugier, Martin Crespi, Nicolás Toro“... in developing this group II intron gene targeting technology for use in eukaryotes, but nuclear genomes present...”
Published 2013-01-01
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643by Myriam Fenina, Dominique Simon-Chazottes, Sandrine Vandormael-Pournin, Jihane Soueid, Francina Langa, Michel Cohen-Tannoudji, Bruno A Bernard, Jean-Jacques Panthier“... was indeed able to introduce a DSB at the Dct locus in live embryonic stem cells. However, the level of gene...”
Published 2012-01-01
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644
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645“..., gene targeting, cloning, and regenerative medicine. However, the majority of attempts to establish ESC...”
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646“... for gene targeting that can also be adapted for multiplexing and other modifications to enable strong...”
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647by Molly DiScala, Matthew S Najor, Timothy Yung, Deri Morgan, Abde M Abukhdeir, Melody A Cobleigh“... cancer, we knocked out both alleles of the STAT6 gene using somatic cell gene targeting. Interestingly...”
Published 2020-01-01
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648“... here facilitates selection of these rare gene targeting events, does not necessitate the systematic PCR...”
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649by Laure M C Leynaud-Kieffer, Samuel C Curran, Irene Kim, Jon K Magnuson, John M Gladden, Scott E Baker, Blake A Simmons“... these challenges, we have developed a simple Cas9-based gene targeting method that provides selectable, iterative...”
Published 2019-01-01
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650by Grzegorz K. Przybylski“... of conditional site- and time-specific Cre-Lox gene targeting technology, allows studying the function of genes...”
Published 2020-04-01
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651“... gene targeting was confirmed by single-cell genotyping and Western blot analysis. Several gene loci...”
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652by Yuka Eura, Hiroji Yanamoto, Yuji Arai, Tomohiko Okuda, Toshiyuki Miyata, Koichi Kokame“... in mammals, we generated Derlin-1-, Derlin-3-, and Herp-deficient mice by gene targeting. Complete loss...”
Published 2012-01-01
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653by Junjie Luo, Zhiyuan Song, Shengli Yu, Dan Cui, Benli Wang, Fangrong Ding, Song Li, Yunping Dai, Ning Li“...Genetically engineered zinc-finger nucleases (ZFNs) are useful for marker-free gene targeting using...”
Published 2014-01-01
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654by Daniel Gomez-Cabello, Sonia Jimeno, María Jesús Fernández-Ávila, Pablo Huertas“..., our findings can be applied to increase gene-targeting efficiency, making it a beneficial tool for a...”
Published 2013-01-01
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655by Masahito Irie, Masanobu Yoshikawa, Ryuichi Ono, Hirotaka Iwafune, Tamio Furuse, Ikuko Yamada, Shigeharu Wakana, Yui Yamashita, Takaya Abe, Fumitoshi Ishino, Tomoko Kaneko-Ishino“...Gene targeting of mouse Sushi-ichi-related retrotransposon homologue 11/Zinc finger CCHC domain...”
Published 2015-09-01
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656by Yoshiro Maezawa, Matthew Binnie, Chengjin Li, Paul Thorner, Chi-Chung Hui, Benjamin Alman, Makoto Mark Taketo, Susan E Quaggin“...Conditional gene targeting in mice has provided great insight into the role of gene function...”
Published 2012-01-01
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657by Asadullah Khusru, Merz Claudia, Neubrandt Luisa, Gust Tatjana C, Zügel Ulrich, von Bonin Arne“... gene targeting approaches.</p> ...”
Published 2008-08-01
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658by Franziska Greulich, Carsten Rudat, Henner F Farin, Vincent M Christoffels, Andreas Kispert“... at different stages of epicardial development. Using a conditional gene targeting approach we find that neither...”
Published 2016-01-01
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659by Anil K Challa, Evan R Boitet, Ashley N Turner, Larry W Johnson, Daniel Kennedy, Ethan R Downs, Katherine M Hymel, Alecia K Gross, Robert A Kesterson“... obtained by chemical mutagenesis and gene targeting. Therefore, most mutations were random and could...”
Published 2016-01-01
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660“... system in combination with transgenic or gene targeting strategy is discussed in further detail....”
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