Perturbation-response genes reveal signaling footprints in cancer gene expression

by Michael Schubert, Bertram Klinger, Martina Klünemann, Anja Sieber, Florian Uhlitz, Sascha Sauer, Mathew J. Garnett, Nils Blüthgen, Julio Saez-Rodriguez
Published 2018-01-01

MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development

by Guillermo E. Parada, Roberto Munita, Ilias Georgakopoulos-Soares, Hugo J. R. Fernandes, Veronika R. Kedlian, Emmanouil Metzakopian, Maria Estela Andres, Eric A. Miska, Martin Hemberg
Published 2021-01-01

Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway

by Annie Wai Yeeng Chai, Pei San Yee, Stacey Price, Shi Mun Yee, Hui Mei Lee, Vivian KH Tiong, Emanuel Gonçalves, Fiona M Behan, Jessica Bateson, James Gilbert, Aik Choon Tan, Ultan McDermott, Mathew J Garnett, Sok Ching Cheong
Published 2020-09-01

CEN‐tools: an integrative platform to identify the contexts of essential genes

by Sumana Sharma, Cansu Dincer, Paula Weidemüller, Gavin J Wright, Evangelia Petsalaki
Published 2020-10-01

Data-deposition protocols for correlative soft X-ray tomography and super-resolution structured illumination microscopy applications

by Andrii Iudin, Ugis Sarkans, Mohamed A. Koronfel, Tom Fish, Ian Dobbie, Maria Harkiolaki, Ardan Patwardhan, Gerard J. Kleywegt
Published 2021-03-01

Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni

by Wannaporn Ittiprasert, Victoria H Mann, Shannon E Karinshak, Avril Coghlan, Gabriel Rinaldi, Geetha Sankaranarayanan, Apisit Chaidee, Toshihiko Tanno, Chutima Kumkhaek, Pannathee Prangtaworn, Margaret M Mentink-Kane, Christina J Cochran, Patrick Driguez, Nancy Holroyd, Alan Tracey, Rutchanee Rodpai, Bart Everts, Cornelis H Hokke, Karl F Hoffmann, Matthew Berriman, Paul J Brindley
Published 2019-01-01

Proteins: interaction at a distance

by Roman A. Laskowski, Janet M. Thornton
Published 2015-11-01

Returning genome sequences to research participants: Policy and practice [version 1; referees: 2 approved]

by Caroline F. Wright, Anna Middleton, Jeffrey C. Barrett, Helen V. Firth, David R. FitzPatrick, Matthew E. Hurles, Michael Parker
Published 2017-02-01

No Evidence of Persistence or Inheritance of Mitochondrial DNA Copy Number in Holocaust Survivors and Their Descendants

by Na Cai, Na Cai, Monika Fňašková, Monika Fňašková, Klára Konečná, Klára Konečná, Miloslava Fojtová, Miloslava Fojtová, Jiří Fajkus, Jiří Fajkus, Eve Coomber, Stephen Watt, Nicole Soranzo, Marek Preiss, Ivan Rektor
Published 2020-03-01

Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines

by Silvia Argimón, Melissa A. L. Masim, June M. Gayeta, Marietta L. Lagrada, Polle K. V. Macaranas, Victoria Cohen, Marilyn T. Limas, Holly O. Espiritu, Janziel C. Palarca, Jeremiah Chilam, Manuel C. Jamoralin, Alfred S. Villamin, Janice B. Borlasa, Agnettah M. Olorosa, Lara F. T. Hernandez, Karis D. Boehme, Benjamin Jeffrey, Khalil Abudahab, Charmian M. Hufano, Sonia B. Sia, John Stelling, Matthew T. G. Holden, David M. Aanensen, Celia C. Carlos
Published 2020-06-01

An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi [version 2; peer review: 2 approved]

by Edward J Marr, Rachel M Milne, Burcu Anar, Gareth Girling, Frank Schwach, Jason P Mooney, Wiebke Nahrendorf, Philip J Spence, Deirdre Cunningham, David A Baker, Jean Langhorne, Julian C Rayner, Oliver Billker, Ellen S Bushell, Joanne Thompson
Published 2020-06-01

An enhanced toolkit for the generation of knockout and marker-free fluorescent Plasmodium chabaudi [version 1; peer review: 2 approved]

by Edward J Marr, Rachel M Milne, Burcu Anar, Gareth Girling, Frank Schwach, Jason P Mooney, Wiebke Nahrendorf, Philip J Spence, Deirdre Cunningham, David A Baker, Jean Langhorne, Julian C Rayner, Oliver Billker, Ellen S Bushell, Joanne Thompson
Published 2020-04-01

Immune Cell Dynamics Unfolded by Single-Cell Technologies

by Daniel J. Kunz, Daniel J. Kunz, Daniel J. Kunz, Tomás Gomes, Kylie R. James
Published 2018-06-01

Functional studies of GWAS variants are gaining momentum

by Florence Lichou, Gosia Trynka
Published 2020-12-01

Single cell transcriptomics comes of age

by Sarah Aldridge, Sarah A. Teichmann
Published 2020-08-01

Global genome diversity of the Leishmania donovani complex

by Susanne U Franssen, Caroline Durrant, Olivia Stark, Bettina Moser, Tim Downing, Hideo Imamura, Jean-Claude Dujardin, Mandy J Sanders, Isabel Mauricio, Michael A Miles, Lionel F Schnur, Charles L Jaffe, Abdelmajeed Nasereddin, Henk Schallig, Matthew Yeo, Tapan Bhattacharyya, Mohammad Z Alam, Matthew Berriman, Thierry Wirth, Gabriele Schönian, James A Cotton
Published 2020-03-01

Repeated clinical malaria episodes are associated with modification of the immune system in children

by Yaw Bediako, Rhys Adams, Adam J. Reid, John Joseph Valletta, Francis M. Ndungu, Jan Sodenkamp, Jedidah Mwacharo, Joyce Mwongeli Ngoi, Domtila Kimani, Oscar Kai, Juliana Wambua, George Nyangweso, Etienne P. de Villiers, Mandy Sanders, Magda Ewa Lotkowska, Jing-Wen Lin, Sarah Manni, John W. G. Addy, Mario Recker, Chris Newbold, Matthew Berriman, Philip Bejon, Kevin Marsh, Jean Langhorne
Published 2019-03-01

The Human Cell Atlas

by Aviv Regev, Sarah A Teichmann, Eric S Lander, Ido Amit, Christophe Benoist, Ewan Birney, Bernd Bodenmiller, Peter Campbell, Piero Carninci, Menna Clatworthy, Hans Clevers, Bart Deplancke, Ian Dunham, James Eberwine, Roland Eils, Wolfgang Enard, Andrew Farmer, Lars Fugger, Berthold Göttgens, Nir Hacohen, Muzlifah Haniffa, Martin Hemberg, Seung Kim, Paul Klenerman, Arnold Kriegstein, Ed Lein, Sten Linnarsson, Emma Lundberg, Joakim Lundeberg, Partha Majumder, John C Marioni, Miriam Merad, Musa Mhlanga, Martijn Nawijn, Mihai Netea, Garry Nolan, Dana Pe'er, Anthony Phillipakis, Chris P Ponting, Stephen Quake, Wolf Reik, Orit Rozenblatt-Rosen, Joshua Sanes, Rahul Satija, Ton N Schumacher, Alex Shalek, Ehud Shapiro, Padmanee Sharma, Jay W Shin, Oliver Stegle, Michael Stratton, Michael J T Stubbington, Fabian J Theis, Matthias Uhlen, Alexander van Oudenaarden, Allon Wagner, Fiona Watt, Jonathan Weissman, Barbara Wold, Ramnik Xavier, Nir Yosef, Human Cell Atlas Meeting Participants
Published 2017-12-01

ELIXIR pilot action: Marine metagenomics – towards a domain specific set of sustainable services [version 1; referees: 1 approved, 2 approved with reservations]

by Espen Mikal Robertsen, Hubert Denise, Alex Mitchell, Robert D. Finn, Lars Ailo Bongo, Nils Peder Willassen
Published 2017-01-01

Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1

by Daniel E. Martin-Herranz, Erfan Aref-Eshghi, Marc Jan Bonder, Thomas M. Stubbs, Sanaa Choufani, Rosanna Weksberg, Oliver Stegle, Bekim Sadikovic, Wolf Reik, Janet M. Thornton
Published 2019-08-01