Characterization of Precursor-Dependent Steroidogenesis in Human Prostate Cancer Models

by Subrata Deb, Steven Pham, Dong-Sheng Ming, Mei Yieng Chin, Hans Adomat, Antonio Hurtado-Coll, Martin E. Gleave, Emma S. Tomlinson Guns
Published 2018-09-01

Computer-Aided Discovery of Small Molecule Inhibitors of Transcriptional Activity of TLX (NR2E1) Nuclear Receptor

by Evgenia Dueva, Kriti Singh, Anastasia Kalyta, Eric LeBlanc, Paul S. Rennie, Artem Cherkasov
Published 2018-11-01

Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer

by Fuqiang Ban, Eric Leblanc, Ayse Derya Cavga, Chia-Chi Flora Huang, Mark R. Flory, Fan Zhang, Matthew E. K. Chang, Hélène Morin, Nada Lallous, Kriti Singh, Martin E. Gleave, Hisham Mohammed, Paul S. Rennie, Nathan A. Lack, Artem Cherkasov
Published 2021-07-01

ONECUT2 is a driver of neuroendocrine prostate cancer

by Haiyang Guo, Xinpei Ci, Musaddeque Ahmed, Junjie Tony Hua, Fraser Soares, Dong Lin, Loredana Puca, Aram Vosoughi, Hui Xue, Estelle Li, Peiran Su, Sujun Chen, Tran Nguyen, Yi Liang, Yuzhe Zhang, Xin Xu, Jing Xu, Anjali V. Sheahan, Wail Ba-Alawi, Si Zhang, Osman Mahamud, Ravi N. Vellanki, Martin Gleave, Robert G. Bristow, Benjamin Haibe-Kains, John T. Poirier, Charles M. Rudin, Ming-Sound Tsao, Bradly G. Wouters, Ladan Fazli, Felix Y. Feng, Leigh Ellis, Theo van der Kwast, Alejandro Berlin, Marianne Koritzinsky, Paul C. Boutros, Amina Zoubeidi, Himisha Beltran, Yuzhuo Wang, Housheng Hansen He
Published 2019-01-01

Immune phenotypes of prostate cancer cells: Evidence of epithelial immune cell-like transition?

by Dong Lin, Xinya Wang, Stephen Yiu Chuen Choi, Xinpei Ci, Xin Dong, Yuzhuo Wang
Published 2016-10-01

Clinic Utilization and Characteristics of Patients Accessing a Prostate Cancer Supportive Care Program’s Sexual Rehabilitation Clinic

by Julie Wong, Luke Witherspoon, Eugenia Wu, Sara Sheikholeslami, Wen Liao, Wallace Yuen, Jenna Bentley, Christine Zarowski, Monita Sundar, Stacy Elliott, Celestia S. Higano, Ryan Flannigan
Published 2020-10-01

Anti-Tumor Effects of Ginsenoside 20(S)-Protopanaxadiol and 1,25-Dihydroxyvitamin D3 Combination in Castration Resistant Prostate Cancer

by Mohamed Ben-Eltriki, Subrata Deb, Gehana Shankar, Gray Meckling, Mohamed Hassona, Takeshi Yamazaki, Ladan Fazli, Mei Yieng Chin, Emma S. Tomlinson Guns
Published 2021-06-01

Computer-Aided Ligand Discovery for Estrogen Receptor Alpha

by Divya Bafna, Fuqiang Ban, Paul S. Rennie, Kriti Singh, Artem Cherkasov
Published 2020-06-01

Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site

by Jaeyong Lee, Liam J. Worrall, Marija Vuckovic, Federico I. Rosell, Francesco Gentile, Anh-Tien Ton, Nathanael A. Caveney, Fuqiang Ban, Artem Cherkasov, Mark Paetzel, Natalie C. J. Strynadka
Published 2020-11-01

Roles of Alternative RNA Splicing of the Bif-1 Gene by SRRM4 During the Development of Treatment-induced Neuroendocrine Prostate Cancer

by Yu Gan, Yinan Li, Zhi Long, Ahn R. Lee, Ning Xie, Jessica M. Lovnicki, Yuxin Tang, Xiang Chen, Jiaoti Huang, Xuesen Dong
Published 2018-05-01

Corrigendum: A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke

by Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Lonna Munro, Kyung Bok Choi, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Timothy Z. Vitalis, Reinhard Gabathuler, Reinhard Gabathuler, Jacob A. Gordon, Jacob A. Gordon, Hans Adomat, Hans Adomat, Emma S.T. Guns, Emma S.T. Guns, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies
Published 2021-05-01

Pre-clinical Models for Malignant Mesothelioma Research: From Chemical-Induced to Patient-Derived Cancer Xenografts

by Noushin Nabavi, Noushin Nabavi, Jingchao Wei, Jingchao Wei, Dong Lin, Dong Lin, Colin C. Collins, Peter W. Gout, Yuzhuo Wang, Yuzhuo Wang
Published 2018-07-01

Semaphorin 3C as a Therapeutic Target in Prostate and Other Cancers

by Daniel H.F. Hui, Kevin J. Tam, Ivy Z.F. Jiao, Christopher J. Ong
Published 2019-02-01

Steroidogenesis in Peripheral and Transition Zones of Human Prostate Cancer Tissue

by Subrata Deb, Mei Yieng Chin, Steven Pham, Hans Adomat, Antonio Hurtado-Coll, Martin E. Gleave, Emma S. Tomlinson Guns
Published 2021-01-01

Lactic Acid and an Acidic Tumor Microenvironment suppress Anticancer Immunity

by Joy X. Wang, Stephen Y.C. Choi, Xiaojia Niu, Ning Kang, Hui Xue, James Killam, Yuzhuo Wang
Published 2020-11-01

Metagenomic and metatranscriptomic analysis of human prostate microbiota from patients with prostate cancer

by Ye Feng, Varune Rohan Ramnarine, Robert Bell, Stanislav Volik, Elai Davicioni, Vanessa M. Hayes, Shancheng Ren, Colin C. Collins
Published 2019-02-01

A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke

by Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Lonna Munro, Kyung Bok Choi, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Reinhard Gabathuler, Reinhard Gabathuler, Jacob A. Gordon, Jacob A. Gordon, Hans Adomat, Hans Adomat, Emma S.T. Guns, Emma S.T. Guns, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies
Published 2021-03-01

Development of secondary urothelial carcinoma following complete response to immune checkpoint inhibitors

by Jean-Michel Lavoie, Gillian Vandekerkhove, Andrew J. Murtha, Gang Wang, Alexander W. Wyatt, Bernhard J. Eigl
Published 2021-11-01

Discovery of a Highly Conserved Peptide in the Iron Transporter Melanotransferrin that Traverses an Intact Blood Brain Barrier and Localizes in Neural Cells

by Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Chaahat S. B. Singh, Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Brett A. Eyford, Thomas Abraham, Lonna Munro, Lonna Munro, Lonna Munro, Lonna Munro, Kyung Bok Choi, Kyung Bok Choi, Kyung Bok Choi, Kyung Bok Choi, Mark Okon, Timothy Z. Vitalis, Reinhard Gabathuler, Reinhard Gabathuler, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Chieh-Ju Lu, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies, Wilfred A. Jefferies
Published 2021-06-01

Potential Therapies for Infectious Diseases Based on Targeting Immune Evasion Mechanisms That Pathogens Have in Common With Cancer Cells

by Jodi Wong, Stephen Yiu Chuen Choi, Stephen Yiu Chuen Choi, Stephen Yiu Chuen Choi, Rongrong Liu, Eddie Xu, Eddie Xu, Eddie Xu, James Killam, Peter W. Gout, Yuzhuo Wang, Yuzhuo Wang, Yuzhuo Wang
Published 2019-02-01