Circulating tumor cell number and endocrine therapy index in ER positive metastatic breast cancer patients

by Costanza Paoletti, Meredith M. Regan, Samuel M. Niman, Emily M. Dolce, Elizabeth P. Darga, Minetta C. Liu, P. Kelly Marcom, Lowell L. Hart, John W. Smith, Karen L. Tedesco, Eitan Amir, Ian E. Krop, Angela M. DeMichele, Pamela J. Goodwin, Margaret Block, Kimberly Aung, Martha E. Brown, Robert T. McCormack, Daniel F. Hayes
Published 2021-06-01

Development and usability testing of HEARTPA♀N: protocol for a mixed methods strategy to develop an integrated smartphone and web-based intervention for women with cardiac pain

by France Légare, Colleen Norris, Michael McGillion, Ann Kristin Bjørnnes, Jennifer Stinson, Abida Dhukai, Lynn Cooper, Joel Katz, Chitra Lalloo, Marit Leegaard, Mike Lovas, Judith McFetridge-Durdle, Laura Parente, Rose Patterson, Leah Pink, Jennifer Price, Akib Uddin, J Charles Victor, Judy Watt-Watson, Carol Auld, Christine Faubert, Deborah Park, Marianne Park, Beatrice Rickard, Vincenza Spiteri DeBonis
Published 2020-03-01

A multi-omics study links TNS3 and SEPT7 to long-term former smoking NSCLC survival

by Sipeng Shen, Yongyue Wei, Yi Li, Weiwei Duan, Xuesi Dong, Lijuan Lin, Dongfang You, Adonina Tardon, Chu Chen, John K. Field, Rayjean J. Hung, Geoffrey Liu, Dakai Zhu, Christopher I. Amos, Li Su, Yang Zhao, Zhibin Hu, Hongbing Shen, Ruyang Zhang, Feng Chen, David C. Christiani
Published 2021-05-01

Scaling up eConsult for access to specialists in primary healthcare across four Canadian provinces: study protocol of a multiple case study

by Mylaine Breton, Mélanie Ann Smithman, Clare Liddy, Erin Keely, Gerard Farrell, Alexander Singer, Catherine Lamoureux-Lamarche, Maxine Dumas Pilon, Véronique Nabelsi, Isabelle Gaboury, Marie-Pierre Gagnon, Carolyn Steele Gray, Jay Shaw, Catherine Hudon, Kris Aubrey-Bassler, Justin Gagnon, Élizabeth Côté-Boileau, Paula Louise Bush
Published 2019-09-01

GSK-3β Contributes to Parkinsonian Dopaminergic Neuron Death: Evidence From Conditional Knockout Mice and Tideglusib

by Junyu Li, Junyu Li, Shanshan Ma, Shanshan Ma, Jingnan Chen, Kunhua Hu, Kunhua Hu, Yongyi Li, Yongyi Li, Zeyu Zhang, Zeyu Zhang, Zixiang Su, Zixiang Su, James R. Woodgett, Mingtao Li, Mingtao Li, Qiaoying Huang, Qiaoying Huang
Published 2020-06-01

Enhancing the uptake of systematic reviews of effects: what is the best format for health care managers and policy-makers? A mixed-methods study

by Christine Marquez, Alekhya Mascarenhas Johnson, Sabrina Jassemi, Jamie Park, Julia E. Moore, Caroline Blaine, Gertrude Bourdon, Mark Chignell, Moriah E. Ellen, Jacques Fortin, Ian D. Graham, Anne Hayes, Jemila Hamid, Brenda Hemmelgarn, Michael Hillmer, Bev Holmes, Jayna Holroyd-Leduc, Linda Hubert, Brian Hutton, Monika Kastner, John N. Lavis, Karen Michell, David Moher, Mathieu Ouimet, Laure Perrier, Andrea Proctor, Thomas Noseworthy, Victoria Schuckel, Sharlene Stayberg, Marcello Tonelli, Andrea C. Tricco, Sharon E. Straus
Published 2018-06-01

Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis

by Kyoko Ito, Joun Lee, Stephanie Chrysanthou, Yilin Zhao, Katherine Josephs, Hiroyo Sato, Julie Teruya-Feldstein, Deyou Zheng, Meelad M. Dawlaty, Keisuke Ito
Published 2019-09-01

A pragmatic randomized control trial and realist evaluation on the implementation and effectiveness of an internet application to support self-management among individuals seeking...

by Jennifer M. Hensel, Jay Shaw, Lianne Jeffs, Noah M. Ivers, Laura Desveaux, Ashley Cohen, Payal Agarwal, Walter P. Wodchis, Joshua Tepper, Darren Larsen, Anita McGahan, Peter Cram, Geetha Mukerji, Muhammad Mamdani, Rebecca Yang, Ivy Wong, Nike Onabajo, Trevor Jamieson, R. Sacha Bhatia
Published 2016-10-01

Protocol for a cluster randomised trial evaluating a multifaceted intervention starting preconceptionally—Early Interventions to Support Trajectories for Healthy Life in India (EIN...

by Cindy-Lee Dennis, Prabhat Jha, Caroline H D Fall, Stephanie Atkinson, Stephen Lye, Stephen G Matthews, Daniel Sellen, Ghattu V Krishnaveni, Kumar Gavali Suryanarayana, Manohar Prabhu Prasad, Antonisamy Belavendra, Ramaswamy Balasubramaniam, Robert H J Bandsma, Giriraj Ratan Chandak, Elena M Comelli, Sandra T Davidge, Geoffrey L Hammond, Sadhana R Joshi, Kang Lee, Patrick McGowan, Pablo Nepomnaschy, Vivek Padvetnaya, Sirazul Ameen Sahariah, Jacquetta Trasler, Chittaranjan S Yajnik, Marie-Claude Martin, Nusrat Husain
Published 2021-02-01

Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals

by Hongjie Chen, Arunabha Majumdar, Lu Wang, Siddhartha Kar, Kevin M. Brown, Helian Feng, Constance Turman, Joe Dennis, Douglas Easton, Kyriaki Michailidou, Jacques Simard, Timothy Bishop, Iona C. Cheng, Jeroen R. Huyghe, Stephanie L. Schmit, Tracy A. O’Mara, Amanda B. Spurdle, Puya Gharahkhani, Johannes Schumacher, Janusz Jankowski, Ines Gockel, Melissa L. Bondy, Richard S. Houlston, Robert B. Jenkins, Beatrice Melin, Corina Lesseur, Andy R. Ness, Brenda Diergaarde, Andrew F. Olshan, Christopher I. Amos, David C. Christiani, Maria T. Landi, James D. McKay, Myriam Brossard, Mark M. Iles, Matthew H. Law, Stuart MacGregor, Jonathan Beesley, Michelle R. Jones, Jonathan Tyrer, Stacey J. Winham, Alison P. Klein, Gloria Petersen, Donghui Li, Brian M. Wolpin, Rosalind A. Eeles, Christopher A. Haiman, Zsofia Kote-Jarai, Fredrick R. Schumacher, Paul Brennan, Stephen J. Chanock, Valerie Gaborieau, Mark P. Purdue, Paul Pharoah, Rayjean J. Hung, Laufey T. Amundadottir, Peter Kraft, Bogdan Pasaniuc, Sara Lindström
Published 2021-07-01

Acute respiratory failure in immunocompromised patients: outcome and clinical features according to neutropenia status

by Djamel Mokart, Michael Darmon, Peter Schellongowski, Peter Pickkers, Marcio Soares, Jordi Rello, Philippe R. Bauer, Andry van de Louw, Virginie Lemiale, Fabio Silvio Taccone, Ignacio Martin-Loeches, Jorge Salluh, Katerina Rusinova, Sangeeta Mehta, Massimo Antonelli, Achille Kouatchet, Andreas Barratt-Due, Miia Valkonen, Precious Pearl Landburg, Ramin Brandt Bukan, Frédéric Pène, Victoria Metaxa, Gaston Burghi, Colombe Saillard, Lene B. Nielsen, Emmanuel Canet, Magali Bisbal, Elie Azoulay, for the Efraim investigators and the Nine-I study group
Published 2020-10-01

Multi-Omics Analysis Reveals a HIF Network and Hub Gene EPAS1 Associated with Lung Adenocarcinoma

by Zhaoxi Wang, Yongyue Wei, Ruyang Zhang, Li Su, Stephanie M. Gogarten, Geoffrey Liu, Paul Brennan, John K. Field, James D. McKay, Jolanta Lissowska, Beata Swiatkowska, Vladimir Janout, Ciprian Bolca, Milica Kontic, Ghislaine Scelo, David Zaridze, Cathy C. Laurie, Kimberly F. Doheny, Elizabeth K. Pugh, Beth A. Marosy, Kurt N. Hetrick, Xiangjun Xiao, Claudio Pikielny, Rayjean J. Hung, Christopher I. Amos, Xihong Lin, David C. Christiani
Published 2018-06-01

Estimating GFR by Serum Creatinine, Cystatin C, and β2-Microglobulin in Older Adults: Results From the Canadian Study of Longevity in Type 1 Diabetes

by Daniel Scarr, Petter Bjornstad, Leif E. Lovblom, Julie A. Lovshin, Genevieve Boulet, Yuliya Lytvyn, Mohammed A. Farooqi, Vesta Lai, Andrej Orszag, Alanna Weisman, Hillary A. Keenan, Michael H. Brent, Narinder Paul, Vera Bril, David Z.I. Cherney, Bruce A. Perkins
Published 2019-06-01

SARS-CoV-2 in Transit: Characterization of SARS-CoV-2 Genomes From Venezuelan Migrants in Colombia

by Luz H. Patiño, Nathalia Ballesteros, Marina Muñoz, Sergio Castañeda, Carolina Hernández, Sergio Gomez, Carolina Florez, Angelica Rico, Liseth Pardo, Carlos E. Hernandez-Pereira, Lourdes Delgado-Noguera, Maria E. Grillet, Matthew M. Hernandez, Zenab Khan, Adriana van de Guchte, Jayeeta Dutta, Ana S Gonzalez-Reiche, Viviana Simon, Harm van Bakel, Emilia Mia Sordillo, Juan David Ramírez, Alberto E. Paniz-Mondolfi
Published 2021-09-01

Prioritizing a Research Agenda of Transitional Care Interventions for Childhood-Onset Disabilities

by Andrea Duncan, Andrea Duncan, Dorothy Luong, Laure Perrier, Mark T. Bayley, Mark T. Bayley, Mark T. Bayley, Gail Andrew, Kelly Arbour-Nicitopoulos, Kelly Arbour-Nicitopoulos, Brian Chan, Brian Chan, C. J. Curran, Gina Dimitropoulos, Laura Hartman, Lennox Huang, Lennox Huang, Monika Kastner, Monika Kastner, Monika Kastner, Shauna Kingsnorth, Shauna Kingsnorth, Anna McCormick, Anna McCormick, Michelle Nelson, Michelle Nelson, David Nicholas, Melanie Penner, Melanie Penner, Melanie Penner, Laura Thompson, Alene Toulany, Alene Toulany, Amanda Woo, Joanne Zee, Joanne Zee, Sarah E. P. Munce, Sarah E. P. Munce, Sarah E. P. Munce
Published 2021-09-01

Evaluation of the association of heterozygous germline variants in NTHL1 with breast cancer predisposition: an international multi-center study of 47,180 subjects

by Na Li, Magnus Zethoven, Simone McInerny, Lisa Devereux, Yu-Kuan Huang, Niko Thio, Dane Cheasley, Sara Gutiérrez-Enríquez, Alejandro Moles-Fernández, Orland Diez, Tu Nguyen-Dumont, Melissa C. Southey, John L. Hopper, Jacques Simard, Martine Dumont, Penny Soucy, Alfons Meindl, Rita Schmutzler, Marjanka K. Schmidt, Muriel A. Adank, Irene L. Andrulis, Eric Hahnen, Christoph Engel, Fabienne Lesueur, Elodie Girard, Susan L. Neuhausen, Elad Ziv, Jamie Allen, Douglas F. Easton, Rodney J. Scott, Kylie L. Gorringe, Paul A. James, Ian G. Campbell
Published 2021-05-01

7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial

by Nick Daneman, Asgar H. Rishu, Ruxandra Pinto, Pierre Aslanian, Sean M. Bagshaw, Alex Carignan, Emmanuel Charbonney, Bryan Coburn, Deborah J. Cook, Michael E. Detsky, Peter Dodek, Richard Hall, Anand Kumar, Francois Lamontagne, Francois Lauzier, John C. Marshall, Claudio M. Martin, Lauralyn McIntyre, John Muscedere, Steven Reynolds, Wendy Sligl, Henry T. Stelfox, M. Elizabeth Wilcox, Robert A. Fowler, on behalf of the Canadian Critical Care Trials Group
Published 2018-02-01

Rare deleterious germline variants and risk of lung cancer

by Yanhong Liu, Jun Xia, James McKay, Spiridon Tsavachidis, Xiangjun Xiao, Margaret R. Spitz, Chao Cheng, Jinyoung Byun, Wei Hong, Yafang Li, Dakai Zhu, Zhuoyi Song, Susan M. Rosenberg, Michael E. Scheurer, Farrah Kheradmand, Claudio W. Pikielny, Christine M. Lusk, Ann G. Schwartz, Ignacio I. Wistuba, Michael H. Cho, Edwin K. Silverman, Joan Bailey-Wilson, Susan M. Pinney, Marshall Anderson, Elena Kupert, Colette Gaba, Diptasri Mandal, Ming You, Mariza de Andrade, Ping Yang, Triantafillos Liloglou, Michael P. A. Davies, Jolanta Lissowska, Beata Swiatkowska, David Zaridze, Anush Mukeria, Vladimir Janout, Ivana Holcatova, Dana Mates, Jelena Stojsic, Ghislaine Scelo, Paul Brennan, Geoffrey Liu, John K. Field, Rayjean J. Hung, David C. Christiani, Christopher I. Amos
Published 2021-02-01

Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation (PERSPECTIVE I&I)

by Jennifer D. Brooks, Hermann H. Nabi, Irene L. Andrulis, Antonis C. Antoniou, Jocelyne Chiquette, Philippe Després, Peter Devilee, Michel Dorval, Arnaud Droit, Douglas F. Easton, Andrea Eisen, Laurence Eloy, Samantha Fienberg, David Goldgar, Eric Hahnen, Yann Joly, Bartha Maria Knoppers, Aisha Lofters, Jean-Yves Masson, Nicole Mittmann, Jean-Sébastien Paquette, Nora Pashayan, Rita Schmutzler, Tracy Stockley, Sean V. Tavtigian, Meghan J. Walker, Michael Wolfson, Anna Maria Chiarelli, Jacques Simard
Published 2021-06-01

Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial

by Philippe Bégin, Jeannie Callum, Nancy M. Heddle, Richard Cook, Michelle P. Zeller, Alan Tinmouth, Dean A. Fergusson, Melissa M. Cushing, Marshall J. Glesby, Michaël Chassé, Dana V. Devine, Nancy Robitalle, Renée Bazin, Nadine Shehata, Andrés Finzi, Allison McGeer, Damon C. Scales, Lisa Schwartz, Alexis F. Turgeon, Ryan Zarychanski, Nick Daneman, Richard Carl, Luiz Amorim, Caroline Gabe, Martin Ellis, Bruce S. Sachais, Kent Cadogan Loftsgard, Erin Jamula, Julie Carruthers, Joanne Duncan, Kayla Lucier, Na Li, Yang Liu, Chantal Armali, Amie Kron, Dimpy Modi, Marie-Christine Auclair, Sabrina Cerro, Meda Avram, Donald M. Arnold
Published 2021-05-01