TNFα secreted by glioma associated macrophages promotes endothelial activation and resistance against anti-angiogenic therapy

by Qingxia Wei, Olivia Singh, Can Ekinci, Jaspreet Gill, Mira Li, Yasin Mamatjan, Shirin Karimi, Severa Bunda, Sheila Mansouri, Kenneth Aldape, Gelareh Zadeh
Published 2021-04-01

Medical Assistance in Dying in patients with advanced cancer and their caregivers: a mixed methods longitudinal study protocol

by Madeline Li, Gilla K. Shapiro, Roberta Klein, Anne Barbeau, Anne Rydall, Jennifer A. H. Bell, Rinat Nissim, Sarah Hales, Camilla Zimmermann, Rebecca K. S. Wong, Gary Rodin
Published 2021-07-01

DOT1L inhibition attenuates graft-versus-host disease by allogeneic T cells in adoptive immunotherapy models

by Yuki Kagoya, Munehide Nakatsugawa, Kayoko Saso, Tingxi Guo, Mark Anczurowski, Chung-Hsi Wang, Marcus O. Butler, Cheryl H. Arrowsmith, Naoto Hirano
Published 2018-05-01

Prediction of Human Papillomavirus (HPV) Association of Oropharyngeal Cancer (OPC) Using Radiomics: The Impact of the Variation of CT Scanner

by Reza Reiazi, Colin Arrowsmith, Mattea Welch, Farnoosh Abbas-Aghababazadeh, Christopher Eeles, Tony Tadic, Andrew J. Hope, Scott V. Bratman, Benjamin Haibe-Kains
Published 2021-05-01

Risk of Thrombosis in Adult Philadelphia-Positive ALL Treated with an Asparaginase-Free ALL Regimen

by Ruiqi Chen, Xing Liu, Arjun D. Law, Solaf Kanfar, Dawn Maze, Steven M. Chan, Vikas Gupta, Karen W. Yee, Mark D. Minden, Aaron D. Schimmer, Andre C. Schuh, Caroline J. McNamara, Tracy Murphy, Anna Xu, Umberto Falcone, Jack Seki, Hassan Sibai
Published 2021-12-01

Cancer patients’ experiences with immune checkpoint modulators: A qualitative study

by Kari Ala‐Leppilampi, Natalie A. Baker, Chris McKillop, Marcus O. Butler, Lillian L. Siu, Anna Spreafico, Albiruni R. Abdul Razak, Anthony M. Joshua, David Hogg, Philippe L. Bedard, Natasha Leighl, Amit M. Oza, Janet A. Parsons, Aaron R. Hansen
Published 2020-05-01

A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia

by Gregory A. Reed, Gary J. Schiller, Suman Kambhampati, Martin S. Tallman, Dan Douer, Mark D. Minden, Karen W. Yee, Vikas Gupta, Joseph Brandwein, Yulia Jitkova, Marcela Gronda, Rose Hurren, Aisha Shamas‐Din, Andre C. Schuh, Aaron D. Schimmer
Published 2016-11-01

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation

by Yoshihito Kano, Teklab Gebregiworgis, Christopher B. Marshall, Nikolina Radulovich, Betty P. K. Poon, Jonathan St-Germain, Jonathan D. Cook, Ivette Valencia-Sama, Benjamin M. M. Grant, Silvia Gabriela Herrera, Jinmin Miao, Brian Raught, Meredith S. Irwin, Jeffrey E. Lee, Jen Jen Yeh, Zhong-Yin Zhang, Ming-Sound Tsao, Mitsuhiko Ikura, Michael Ohh
Published 2019-01-01

Precision histology: how deep learning is poised to revitalize histomorphology for personalized cancer care

by Ugljesa Djuric, Gelareh Zadeh, Kenneth Aldape, Phedias Diamandis
Published 2017-06-01

Interleukin-15 in cancer immunotherapy: IL-15 receptor complex versus soluble IL-15 in a cancer cell-delivered murine leukemia model

by Alexandra Berger, Sarah J. Colpitts, Melanie S. S. Seabrook, Caren L. Furlonger, Maura B. Bendix, Joshua M. Moreau, William M. McKillop, Jeffrey A. Medin, Christopher J. Paige
Published 2019-12-01

Development of a psychoeducational intervention for people affected by pancreatic cancer

by Eryn Tong, Chris Lo, Shari Moura, Kelly Antes, Sarah Buchanan, Venissa Kamtapersaud, Gerald M. Devins, Camilla Zimmermann, Steven Gallinger, Gary Rodin
Published 2019-06-01

The predictive value of nadir neutrophil count during treatment of cervical cancer: Interactions with tumor hypoxia and interstitial fluid pressure (IFP)

by Rachel Glicksman, Naz Chaudary, Melania Pintilie, Eric Leung, Blaise Clarke, Kieyan Sy, Richard P. Hill, Kathy Han, Anthony Fyles, Michael Milosevic
Published 2017-10-01

Metabolic targeting of HIF-dependent glycolysis reduces lactate, increases oxygen consumption and enhances response to high-dose single-fraction radiotherapy in hypoxic solid tumor...

by Eric Leung, Rob A. Cairns, Naz Chaudary, Ravi N. Vellanki, Tuula Kalliomaki, Eduardo H. Moriyama, Hilda Mujcic, Brian C. Wilson, Bradly G. Wouters, Richard Hill, Michael Milosevic
Published 2017-06-01

Evidence-based region of interest matching guidelines for sarcoma volumetric image-guided radiation therapy

by Winnie Li, Samuel Appiah, Christine Hill, Nathan Becker, Charles Catton, Peter Chung, David Shultz, Peter Ferguson, Brian O'Sullivan, Colleen Dickie
Published 2018-03-01

Long-term patient-reported distress in locally advanced cervical cancer patients treated with definitive chemoradiation

by Jessica L. Conway, Shira Felder, Jiayin Tang, Jelena Lukovic, Kathy Han, Zhihui Liu, Michael Milosevic, Anthony Fyles, Jennifer Croke
Published 2020-07-01

Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma

by Moustafa Abdalla, Danh Tran-Thanh, Juan Moreno, Vladimir Iakovlev, Ranju Nair, Nisha Kanwar, Mohamed Abdalla, Jennifer P. Y. Lee, Jennifer Yin Yee Kwan, Thomas R. Cawthorn, Keisha Warren, Nona Arneson, Dong-Yu Wang, Natalie S. Fox, Bruce J. Youngson, Naomi A. Miller, Alexandra M. Easson, David McCready, Wey L. Leong, Paul C. Boutros, Susan J. Done
Published 2017-11-01

Cerebral organoids: emerging ex vivo humanoid models of glioblastoma

by Michail-Dimitrios Papaioannou, Kevin Sangster, Rifat Shahriar Sajid, Ugljesa Djuric, Phedias Diamandis
Published 2020-12-01

Somatic Alteration Burden Involving Non-Cancer Genes Predicts Prognosis in Early-Stage Non-Small Cell Lung Cancer

by Dennis Wang, Nhu-An Pham, Timothy M. Freeman, Vibha Raghavan, Roya Navab, Jonathan Chang, Chang-Qi Zhu, Dalam Ly, Jiefei Tong, Bradly G. Wouters, Melania Pintilie, Michael F. Moran, Geoffrey Liu, Frances A. Shepherd, Ming-Sound Tsao
Published 2019-07-01

Surgical site infections following oral cavity cancer resection and reconstruction is a risk factor for plate exposure

by Christopher M. Yao, Hedyeh Ziai, Gordon Tsang, Andrea Copeland, Dale Brown, Jonathan C. Irish, Ralph W. Gilbert, David P. Goldstein, Patrick J. Gullane, John R. de Almeida
Published 2017-04-01

Evolution of AF6-RAS association and its implications in mixed-lineage leukemia

by Matthew J. Smith, Elizabeth Ottoni, Noboru Ishiyama, Marilyn Goudreault, André Haman, Claus Meyer, Monika Tucholska, Genevieve Gasmi-Seabrook, Serena Menezes, Rob C. Laister, Mark D. Minden, Rolf Marschalek, Anne-Claude Gingras, Trang Hoang, Mitsuhiko Ikura
Published 2017-10-01