Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis

by Minoru Inoue, Ryota Nakashima, Masahiro Enomoto, Yuhki Koike, Xiao Zhao, Kenneth Yip, Shao Hui Huang, John N. Waldron, Mitsuhiko Ikura, Fei-Fei Liu, Scott V. Bratman
Published 2018-11-01

Landscape mapping of shared antigenic epitopes and their cognate TCRs of tumor-infiltrating T lymphocytes in melanoma

by Kenji Murata, Munehide Nakatsugawa, Muhammed A Rahman, Linh T Nguyen, Douglas G Millar, David T Mulder, Kenji Sugata, Hiroshi Saijo, Yukiko Matsunaga, Yuki Kagoya, Tingxi Guo, Mark Anczurowski, Chung-Hsi Wang, Brian D Burt, Dalam Ly, Kayoko Saso, Alexandra Easson, David P Goldstein, Michael Reedijk, Danny Ghazarian, Trevor J Pugh, Marcus O Butler, Tak W Mak, Pamela S Ohashi, Naoto Hirano
Published 2020-04-01

Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors

by S. Y. Cindy Yang, Stephanie Lheureux, Katherine Karakasis, Julia V. Burnier, Jeffery P. Bruce, Derek L. Clouthier, Arnavaz Danesh, Rene Quevedo, Mark Dowar, Youstina Hanna, Tiantian Li, Lin Lu, Wei Xu, Blaise A. Clarke, Pamela S. Ohashi, Patricia A. Shaw, Trevor J. Pugh, Amit M. Oza
Published 2018-10-01

Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells

by Evelyne Lima-Fernandes, Alex Murison, Tiago da Silva Medina, Yadong Wang, Anqi Ma, Cherry Leung, Genna M. Luciani, Jennifer Haynes, Aaron Pollett, Constanze Zeller, Shili Duan, Antonija Kreso, Dalia Barsyte-Lovejoy, Bradly G. Wouters, Jian Jin, Daniel D. De Carvalho, Mathieu Lupien, Cheryl H. Arrowsmith, Catherine A. O’Brien
Published 2019-03-01

Durable therapeutic gain despite competing mortality in long-term follow-up of a randomized hyperfractionated radiotherapy trial for locally advanced head and neck cancer

by Brian O'Sullivan, Shao Hui Huang, Thomas Keane, Wei Xu, Jie Su, John Waldron, Patrick Gullane, Fei-Fei Liu, Padraig Warde, David Payne, Li Tong, Bernard Cummings
Published 2020-03-01

831 E3 ubiquitin ligase Cbl-b deficient CD8+ T cells overcome Treg cell-mediated suppression through IFN-γ and induce robust anti-tumor immunity

by SeongJun Han, Zhe Qi Liu, Douglas Chung, Michael St Paul, Carlos Garcia-Batres, Azin Sayad, Alisha Elford, Matthew Gold, Natasha Grimshaw, Pamela Ohashi
Published 2020-11-01

Malignant Bowel Obstruction in Advanced Gynecologic Cancers: An Updated Review from a Multidisciplinary Perspective

by Yeh Chen Lee, Nazlin Jivraj, Catherine O’Brien, Tanya Chawla, Eran Shlomovitz, Sarah Buchanan, Jenny Lau, Jennifer Croke, Johane P. Allard, Preeti Dhar, Stephane Laframboise, Sarah E. Ferguson, Neesha Dhani, Marcus Butler, Pamela Ng, Terri Stuart-McEwan, Pamela Savage, Lisa Tinker, Amit M. Oza, Stephanie Lheureux
Published 2018-01-01

HLA-DP84Gly constitutively presents endogenous peptides generated by the class I antigen processing pathway

by Yuki Yamashita, Mark Anczurowski, Munehide Nakatsugawa, Makito Tanaka, Yuki Kagoya, Ankit Sinha, Kenji Chamoto, Toshiki Ochi, Tingxi Guo, Kayoko Saso, Marcus O. Butler, Mark D. Minden, Thomas Kislinger, Naoto Hirano
Published 2017-05-01

Addendum: MacDonald, A.M., et al. CaRE @ Home: Pilot Study of an Online Multidimensional Cancer Rehabilitation and Exercise Program for Cancer Survivors. <i>J. Clin. Med.</i> 2020,...

by Anne Marie MacDonald, Aleksandra Chafranskaia, Christian J. Lopez, Manjula Maganti, Lori J. Bernstein, Eugene Chang, David Michael Langelier, Maya Obadia, Beth Edwards, Paul Oh, Jacqueline L. Bender, Shabbir M.H. Alibhai, Jennifer M. Jones
Published 2020-10-01

Additional germline findings from a tumor profiling program

by Neda Stjepanovic, Tracy L. Stockley, Philippe L. Bedard, Jeanna M. McCuaig, Melyssa Aronson, Spring Holter, Kara Semotiuk, Natasha B. Leighl, Raymond Jang, Monika K. Krzyzanowska, Amit M. Oza, Abha Gupta, Christine Elser, Lailah Ahmed, Lisa Wang, Suzanne Kamel-Reid, Lillian L. Siu, Raymond H. Kim
Published 2018-08-01

Real‐world health utility scores and toxicities to tyrosine kinase inhibitors in epidermal growth factor receptor mutated advanced non‐small cell lung cancer

by Shirley Xue Jiang, Ryan N. Walton, Katrina Hueniken, Justine Baek, Alexandra McCartney, Catherine Labbé, Elliot Smith, Sze Wah Samuel Chan, RuiQi Chen, Catherine Brown, Devalben Patel, Mindy Liang, Lawson Eng, Adrian Sacher, Penelope Bradbury, Natasha B. Leighl, Frances A. Shepherd, Wei Xu, Geoffrey Liu, Manjusha Hurry, Grainne M. O'Kane
Published 2019-12-01

Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial

by Tracy L. Stockley, Amit M. Oza, Hal K. Berman, Natasha B. Leighl, Jennifer J. Knox, Frances A. Shepherd, Eric X. Chen, Monika K. Krzyzanowska, Neesha Dhani, Anthony M. Joshua, Ming-Sound Tsao, Stefano Serra, Blaise Clarke, Michael H. Roehrl, Tong Zhang, Mahadeo A. Sukhai, Nadia Califaretti, Mateya Trinkaus, Patricia Shaw, Theodorus van der Kwast, Lisa Wang, Carl Virtanen, Raymond H. Kim, Albiruni R. A. Razak, Aaron R. Hansen, Celeste Yu, Trevor J. Pugh, Suzanne Kamel-Reid, Lillian L. Siu, Philippe L. Bedard
Published 2016-10-01

Neurological Death is Common in Patients With EGFR Mutant Non-Small Cell Lung Cancer Diagnosed With Brain Metastases

by Matthew Ramotar, HBSc, Sierra Barnes, BSc, Fabio Moraes, MD, Archya Dasgupta, MD, Normand Laperriere, MD, Barbara-Ann Millar, MBChB, Alejandro Berlin, MD, MSc, Tatiana Conrad, MD, Monique van Prooijen, PhD, Andrei Damyanovich, PhD, Robert Heaton, PhD, Young-Bin Cho, PhD, Catherine Coolens, PhD, Geoffrey Liu, MSc, MD, Frances A. Shepherd, MD, Penelope Bradbury, MBChB, Natasha Leighl, MSc, MD, Mark Bernstein, MD, MSc, Gelareh Zadeh, MD, PhD, Paul Kongkham, MD, PhD, Mark Doherty, MB, BCh, BAO, David B. Shultz, MD, PhD
Published 2020-05-01

Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers

by Nhu-An Pham, Nikolina Radulovich, Emin Ibrahimov, Sebastiao N. Martins-Filho, Quan Li, Melania Pintilie, Jessica Weiss, Vibha Raghavan, Michael Cabanero, Robert E. Denroche, Julie M. Wilson, Cristiane Metran-Nascente, Ayelet Borgida, Shawn Hutchinson, Anna Dodd, Michael Begora, Dianne Chadwick, Stefano Serra, Jennifer J. Knox, Steven Gallinger, David W. Hedley, Lakshmi Muthuswamy, Ming-Sound Tsao
Published 2021-05-01

Statistical fundamentals on cancer research for clinicians: Working with your statisticians

by Wei Xu, Shao Hui Huang, Jie Su, Shivakumar Gudi, Brian O'Sullivan
Published 2021-03-01

Clinicopathologic factors that influence prognosis and survival outcomes in men with metastatic castration‐resistant prostate cancer treated with Radium‐223

by Esmail M. Al‐Ezzi, Husam A. Alqaisi, Marco A. J. Iafolla, Lisa Wang, Srikala S. Sridhar, Adrian G. Sacher, Nazanin Fallah‐Rad, Di M. Jiang, Geoffrey A. Watson, Charles N. Catton, Padraig R. Warde, Rob J. Hamilton, Neil E. Fleshner, Alexandre R. Zlotta, Aaron R. Hansen
Published 2021-09-01

Surveillance and outcomes after curative resection for gastroesophageal adenocarcinoma

by Di M. Jiang, Chihiro Suzuki, Osvaldo Espin‐Garcia, Charles H. Lim, Lucy X. Ma, Peiran Sun, Hao‐Wen Sim, Akina Natori, Bryan A. Chan, Stephanie Moignard, Eric X. Chen, Geoffrey Liu, Carol J. Swallow, Gail E. Darling, Rebecca Wong, Raymond W. Jang, Elena Elimova
Published 2020-05-01

Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor

by Rene Quevedo, Anna Spreafico, Jeff Bruce, Arnavaz Danesh, Samah El Ghamrasni, Amanda Giesler, Youstina Hanna, Cherry Have, Tiantian Li, S. Y. Cindy Yang, Tong Zhang, Sylvia L. Asa, Benjamin Haibe-Kains, Monika Krzyzanowska, Adam C. Smith, Simron Singh, Lillian L. Siu, Trevor J. Pugh
Published 2020-04-01

Can TP53 variant negative be high-grade serous ovarian carcinoma? A case series

by Lawrence Kasherman, Swati Garg, Nairi Tchrakian, Blaise Clarke, Katherine Karakasis, Raymond H. Kim, Tracy L. Stockley, Neesha Dhani, Amit M. Oza, Stephanie Lheureux
Published 2021-05-01

Computer-assisted image analysis of the tumor microenvironment on an oral tongue squamous cell carcinoma tissue microarray

by Sangjune Laurence Lee, Michael Cabanero, Martin Hyrcza, Marcus Butler, Fei-Fei Liu, Aaron Hansen, Shao Hui Huang, Ming-Sound Tsao, Yuyao Song, Lin Lu, Wei Xu, Douglas B. Chepeha, David P. Goldstein, Ilan Weinreb, Scott V. Bratman
Published 2019-07-01