Misregulation of the IgH Locus in Thymocytes

by Gita Kumari, Tatiana Gerasimova, Hansen Du, Supriyo De, William H. Wood, Kevin G. Becker, Ranjan Sen
Published 2018-11-01

Tau pathology in cognitively normal older adults

by Jacob Ziontz, Murat Bilgel, Andrea T. Shafer, Abhay Moghekar, Wendy Elkins, Jessica Helphrey, Gabriela Gomez, Danielle June, Michael A. McDonald, Robert F. Dannals, Babak Behnam Azad, Luigi Ferrucci, Dean F. Wong, Susan M. Resnick
Published 2019-12-01

Pancreas++ : Automated Quantification of Pancreatic Islet Cells in Microscopy Images

by Hongyu eChen, Bronwen eMartin, Huan eCai, Jennifer L Fiori, Josephine M Egan, Sana eSiddiqui, Stuart eMaudsley
Published 2013-01-01

Pregabalin suppresses calcium-mediated proteolysis and improves stroke outcome

by Jeong Seon Yoon, Jong-Hwan Lee, Tae Gen Son, Mohamed R. Mughal, Nigel H. Greig, Mark P. Mattson
Published 2011-03-01

Investigation of the association between cerebral iron content and myelin content in normative aging using quantitative magnetic resonance neuroimaging

by Nikkita Khattar, Curtis Triebswetter, Matthew Kiely, Luigi Ferrucci, Susan M. Resnick, Richard G. Spencer, Mustapha Bouhrara
Published 2021-10-01

Health benefits of late-onset metformin treatment every other week in mice

by Irene Alfaras, Sarah J. Mitchell, Hector Mora, Darisbeth Rosario Lugo, Alessandra Warren, Ignacio Navas-Enamorado, Vickie Hoffmann, Christopher Hine, James R. Mitchell, David G. Le Couteur, Victoria C. Cogger, Michel Bernier, Rafael de Cabo
Published 2017-11-01

Conserved and species-specific molecular denominators in mammalian skeletal muscle aging

by Evi M. Mercken, Miriam Capri, Bethany A. Carboneau, Maria Conte, Juliana Heidler, Aurelia Santoro, Alejandro Martin-Montalvo, Marta Gonzalez-Freire, Husam Khraiwesh, José A. González-Reyes, Ruin Moaddel, Yongqing Zhang, Kevin G. Becker, José M. Villalba, Julie A. Mattison, Ilka Wittig, Claudio Franceschi, Rafael de Cabo
Published 2017-05-01

Exploring dementia and neuronal ceroid lipofuscinosis genes in 100 FTD-like patients from 6 towns and rural villages on the Adriatic Sea cost of Apulia

by Celeste Sassi, Rosa Capozzo, Monia Hammer, Chiara Zecca, Monica Federoff, Cornelis Blauwendraat, Nick Bernstein, Jinhui Ding, J. Raphael Gibbs, Timothy Price, Andrew Singleton, Giancarlo Logroscino
Published 2021-03-01

Ezh2 Regulates Activation-Induced CD8+ T Cell Cycle Progression via Repressing Cdkn2a and Cdkn1c Expression

by Guobing Chen, Kalpana Subedi, Sayantan Chakraborty, Alexie Sharov, Jian Lu, Jaekwan Kim, Xiaofan Mi, Robert Wersto, Myong-Hee Sung, Nan-ping Weng
Published 2018-03-01

Central Role of the EGF Receptor in Neurometabolic Aging

by Sana Siddiqui, Meng Fang, Bin Ni, Daoyuan Lu, Bronwen Martin, Stuart Maudsley
Published 2012-01-01

Overexpression of a Neuronal Type Adenylyl Cyclase (Type 8) in Sinoatrial Node Markedly Impacts Heart Rate and Rhythm

by Jack M. Moen, Jack M. Moen, Michael G. Matt, Michael G. Matt, Christopher Ramirez, Kirill V. Tarasov, Khalid Chakir, Yelena S. Tarasova, Yevgeniya Lukyanenko, Kenta Tsutsui, Oliver Monfredi, Oliver Monfredi, Christopher H. Morrell, Christopher H. Morrell, Syevda Tagirova, Yael Yaniv, Thanh Huynh, Karel Pacak, Ismayil Ahmet, Edward G. Lakatta
Published 2019-06-01

MicroRNAs Modulate Oxidative Stress in Hypertension through PARP-1 Regulation

by Douglas F. Dluzen, Yoonseo Kim, Paul Bastian, Yongqing Zhang, Elin Lehrmann, Kevin G. Becker, Nicole Noren Hooten, Michele K. Evans
Published 2017-01-01

Effects of repetitive Transcranial Magnetic Stimulation in aged rats depend on pre-treatment cognitive status: Toward individualized intervention for successful cognitive aging

by Marina Weiler, Perla Moreno-Castilla, Hannah M. Starnes, Edward L.R. Melendez, Kevin C. Stieger, Jeffrey M. Long, Peter R. Rapp
Published 2021-09-01

Systematic Identification of circRNAs in Alzheimer’s Disease

by Kyle R. Cochran, Kirtana Veeraraghavan, Gautam Kundu, Krystyna Mazan-Mamczarz, Christopher Coletta, Madhav Thambisetty, Myriam Gorospe, Supriyo De
Published 2021-08-01

Generation of fourteen isogenic cell lines for Parkinson’s disease-associated leucine-rich repeat kinase (LRRK2)

by Aleksandra Beylina, Rebekah G. Langston, Dorien Rosen, Xylena Reed, Mark R. Cookson
Published 2021-05-01

Mammalian γ2 AMPK regulates intrinsic heart rate

by Arash Yavari, Mohamed Bellahcene, Annalisa Bucchi, Syevda Sirenko, Katalin Pinter, Neil Herring, Julia J. Jung, Kirill V. Tarasov, Emily J. Sharpe, Markus Wolfien, Gabor Czibik, Violetta Steeples, Sahar Ghaffari, Chinh Nguyen, Alexander Stockenhuber, Joshua R. St. Clair, Christian Rimmbach, Yosuke Okamoto, Dongmei Yang, Mingyi Wang, Bruce D. Ziman, Jack M. Moen, Daniel R. Riordon, Christopher Ramirez, Manuel Paina, Joonho Lee, Jing Zhang, Ismayil Ahmet, Michael G. Matt, Yelena S. Tarasova, Dilair Baban, Natasha Sahgal, Helen Lockstone, Rathi Puliyadi, Joseph de Bono, Owen M. Siggs, John Gomes, Hannah Muskett, Mahon L. Maguire, Youlia Beglov, Matthew Kelly, Pedro P. N. dos Santos, Nicola J. Bright, Angela Woods, Katja Gehmlich, Henrik Isackson, Gillian Douglas, David J. P. Ferguson, Jürgen E. Schneider, Andrew Tinker, Olaf Wolkenhauer, Keith M. Channon, Richard J. Cornall, Eduardo B. Sternick, David J. Paterson, Charles S. Redwood, David Carling, Catherine Proenza, Robert David, Mirko Baruscotti, Dario DiFrancesco, Edward G. Lakatta, Hugh Watkins, Houman Ashrafian
Published 2017-11-01

Parkinson’s disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging

by Xi Chen, Chengsong Xie, Wotu Tian, Lixin Sun, Zheng Wang, Sarah Hawes, Lisa Chang, Justin Kung, Jinhui Ding, Shengdi Chen, Weidong Le, Huaibin Cai
Published 2020-02-01

Aging- and gender-related modulation of RAAS: potential implications in COVID-19 disease

by Laura Monteonofrio, Maria Cristina Florio, Majd AlGhatrif, Edward G Lakatta, Maurizio C Capogrossi
Published 2021-01-01

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models

by Michiyo Iba, Changyoun Kim, Michelle Sallin, Somin Kwon, Anjali Verma, Cassia Overk, Robert A. Rissman, Ranjan Sen, Jyoti Misra Sen, Eliezer Masliah
Published 2020-07-01

Blood Metabolite Signature of Metabolic Syndrome Implicates Alterations in Amino Acid Metabolism: Findings from the Baltimore Longitudinal Study of Aging (BLSA) and the Tsuruoka Me...

by Jackson A. Roberts, Vijay R. Varma, Chiung-Wei Huang, Yang An, Anup Oommen, Toshiko Tanaka, Luigi Ferrucci, Palchamy Elango, Toru Takebayashi, Sei Harada, Miho Iida, Madhav Thambisetty
Published 2020-02-01