PU.1 Level-Directed Chromatin Structure Remodeling at the Irf8 Gene Drives Dendritic Cell Commitment

by Jörg Schönheit, Christiane Kuhl, Marie Luise Gebhardt, Francisco Fernández Klett, Pia Riemke, Marina Scheller, Gang Huang, Ronald Naumann, Achim Leutz, Carol Stocking, Josef Priller, Miguel A. Andrade-Navarro, Frank Rosenbauer
Published 2013-05-01

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus.

by Deborah S Cunninghame Graham, David L Morris, Tushar R Bhangale, Lindsey A Criswell, Ann-Christine Syvänen, Lars Rönnblom, Timothy W Behrens, Robert R Graham, Timothy J Vyse
Published 2011-10-01

Transcription factor IRF1 is responsible for IRF8-mediated IL-1β expression in reactive microglia

by Takahiro Masuda, Shosuke Iwamoto, Satsuki Mikuriya, Hidetoshi Tozaki-Saitoh, Tomohiko Tamura, Makoto Tsuda, Kazuhide Inoue
Published 2015-08-01

IRF3 and IRF8 Regulate NF-κB Signaling by Targeting MyD88 in Teleost Fish

by Xiaolong Yan, Xiaolong Yan, Xueyan Zhao, Ruixuan Huo, Tianjun Xu, Tianjun Xu, Tianjun Xu, Tianjun Xu, Tianjun Xu
Published 2020-04-01

Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency

by Gumez Audrey, Carthagéna Laëtitia, Delcroix-Genête Delphine, Munier Sandie, Hazan Uriel
Published 2005-11-01

IRF8 governs expression of genes involved in innate and adaptive immunity in human and mouse germinal center B cells.

by Dong-Mi Shin, Chang-Hoon Lee, Herbert C Morse
Published 2011-01-01

IRF-8 Controls Melanoma Progression by Regulating the Cross Talk between Cancer and Immune Cells within the Tumor Microenvironment

by Fabrizio Mattei, Giovanna Schiavoni, Paola Sestili, Francesca Spadaro, Alessandra Fragale, Antonella Sistigu, Valeria Lucarini, Massimo Spada, Massimo Sanchez, Stefania Scala, Angela Battistini, Filippo Belardelli, Lucia Gabriele
Published 2012-12-01

PU.1 and IRF8 Modulate Activation of NLRP3 Inflammasome via Regulating Its Expression in Human Macrophages

by Takuya Yashiro, Machiko Yamamoto, Sanae Araumi, Mutsuko Hara, Kyoko Yogo, Koichiro Uchida, Kazumi Kasakura, Chiharu Nishiyama
Published 2021-04-01

Cordycepin Prevents Bone Loss through Inhibiting Osteoclastogenesis by Scavenging ROS Generation

by Ce Dou, Zhen Cao, Ning Ding, Tianyong Hou, Fei Luo, Fei Kang, Xiaochao Yang, Hong Jiang, Zhao Xie, Min Hu, Jianzhong Xu, Shiwu Dong
Published 2016-04-01

SENP3 Suppresses Osteoclastogenesis by De-conjugating SUMO2/3 from IRF8 in Bone Marrow-Derived Monocytes

by Yongxing Zhang, Kai Yang, Jie Yang, Yimin Lao, Lianfu Deng, Guoying Deng, Jing Yi, Xuxu Sun, Qiugen Wang
Published 2020-02-01

IRF8 Impacts Self‐Renewal of Hematopoietic Stem Cells by Regulating TLR9 Signaling Pathway of Innate Immune Cells

by Donghe Li, Yuyin Zhang, Qingsong Qiu, Jinzeng Wang, Xuemei Zhao, Bo Jiao, Xiuli Zhang, Shanhe Yu, Pengfei Xu, Yuqing Dan, Xinhua Xiao, Peihong Wang, Mingzhu Liu, Zhizhou Xia, Zhangsen Huang, Ruihong Zhang, Jiaoyang Li, Xi Xie, Yan Zhang, Chenxuan Liu, Ping Liu, Ruibao Ren
Published 2021-10-01

The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study.

by International Multiple Sclerosis Genetics Consortium
Published 2011-04-01

Tumor-associated macrophage expression of interferon regulatory Factor-8 (IRF8) is a predictor of progression and patient survival in renal cell carcinoma

by Jason B. Muhitch, Nicholas C. Hoffend, Gissou Azabdaftari, Austin Miller, Wiam Bshara, Carl D. Morrison, Thomas Schwaab, Scott I. Abrams
Published 2019-06-01

Cooperative contributions of Interferon regulatory factor 1 (IRF1) and IRF8 to interferon-γ-mediated cytotoxic effects on oligodendroglial progenitor cells

by Pleasure David, Itoh Aki, Horiuchi Makoto, Ozato Keiko, Itoh Takayuki
Published 2011-01-01

High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

by Gerardo Gatti, Courtney Betts, Darío Rocha, Maribel Nicola, Verónica Grupe, Cecilia Ditada, Nicolas G. Nuñez, Emiliano Roselli, Paula Araya, Jeremías Dutto, Lucia Boffelli, Elmer Fernández, Lisa M. Coussens, Mariana Maccioni
Published 2021-03-01

Ferulic acid attenuates microglia-mediated neuroinflammation in retinal degeneration

by Xiaowei Sun, Peng Sun, Limei Liu, Pengfei Jiang, Yuanbin Li
Published 2021-01-01

Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells.

by Lin Sun, Anthony J St Leger, Cheng-Rong Yu, Chang He, Rashid M Mahdi, Chi-Chao Chan, Hongsheng Wang, Herbert C Morse, Charles E Egwuagu
Published 2016-01-01

Correction to: High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

by Gerardo Gatti, Courtney Betts, Darío Rocha, Maribel Nicola, Verónica Grupe, Cecilia Ditada, Nicolas G. Nuñez, Emiliano Roselli, Paula Araya, Jeremías Dutto, Lucia Boffelli, Elmer Fernández, Lisa M. Coussens, Mariana Maccioni
Published 2021-04-01