Rescue of conformational dynamics in enzyme catalysis by directed evolution

by Renee Otten, Lin Liu, Lillian R. Kenner, Michael W. Clarkson, David Mavor, Dan S. Tawfik, Dorothee Kern, James S. Fraser
Published 2018-04-01

Dose-dependent action of the RNA binding protein FOX-1 to relay X-chromosome number and determine C. elegans sex

by Behnom Farboud, Catherine S Novak, Monique Nicoll, Alyssa Quiogue, Barbara J Meyer
Published 2020-12-01

The manifold actions of signaling peptides on subcellular dynamics of a receptor specify stomatal cell fate

by Xingyun Qi, Akira Yoshinari, Pengfei Bai, Michal Maes, Scott M Zeng, Keiko U Torii
Published 2020-08-01

Rhabdo-immunodeficiency virus, a murine model of acute HIV-1 infection

by Rachel A Liberatore, Emily J Mastrocola, Elena Cassella, Fabian Schmidt, Jessie R Willen, Dennis Voronin, Trinity M Zang, Theodora Hatziioannou, Paul D Bieniasz
Published 2019-10-01

Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells

by Kathryn E Kistler, Tatjana Trcek, Thomas R Hurd, Ruoyu Chen, Feng-Xia Liang, Joseph Sall, Masato Kato, Ruth Lehmann
Published 2018-09-01

Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling

by Xingyun Qi, Soon-Ki Han, Jonathan H Dang, Jacqueline M Garrick, Masaki Ito, Alex K Hofstetter, Keiko U Torii
Published 2017-03-01

An intersectional gene regulatory strategy defines subclass diversity of C. elegans motor neurons

by Paschalis Kratsios, Sze Yen Kerk, Catarina Catela, Joseph Liang, Berta Vidal, Emily A Bayer, Weidong Feng, Estanisla Daniel De La Cruz, Laura Croci, G Giacomo Consalez, Kota Mizumoto, Oliver Hobert
Published 2017-07-01

Differential 3’ processing of specific transcripts expands regulatory and protein diversity across neuronal cell types

by Saša Jereb, Hun-Way Hwang, Eric Van Otterloo, Eve-Ellen Govek, John J Fak, Yuan Yuan, Mary E Hatten, Robert B Darnell
Published 2018-03-01

Chimeric antigen receptors that trigger phagocytosis

by Meghan A Morrissey, Adam P Williamson, Adriana M Steinbach, Edward W Roberts, Nadja Kern, Mark B Headley, Ronald D Vale
Published 2018-06-01

Global biogeographic sampling of bacterial secondary metabolism

by Zachary Charlop-Powers, Jeremy G Owen, Boojala Vijay B Reddy, Melinda A Ternei, Denise O Guimarães, Ulysses A de Frias, Monica T Pupo, Prudy Seepe, Zhiyang Feng, Sean F Brady
Published 2015-01-01

Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes

by Roberto Bonasio, Emilio Lecona, Varun Narendra, Philipp Voigt, Fabio Parisi, Yuval Kluger, Danny Reinberg
Published 2014-07-01

The membrane-associated proteins FCHo and SGIP are allosteric activators of the AP2 clathrin adaptor complex

by Gunther Hollopeter, Jeffrey J Lange, Ying Zhang, Thien N Vu, Mingyu Gu, Michael Ailion, Eric J Lambie, Brian D Slaughter, Jay R Unruh, Laurence Florens, Erik M Jorgensen
Published 2014-10-01

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

by Yuan Zhang, Yang Xie, Eric D Berglund, Katie Colbert Coate, Tian Teng He, Takeshi Katafuchi, Guanghua Xiao, Matthew J Potthoff, Wei Wei, Yihong Wan, Ruth T Yu, Ronald M Evans, Steven A Kliewer, David J Mangelsdorf
Published 2012-10-01

Non-canonical TAF complexes regulate active promoters in human embryonic stem cells

by Glenn A Maston, Lihua Julie Zhu, Lynn Chamberlain, Ling Lin, Minggang Fang, Michael R Green
Published 2012-11-01

TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase

by Jing Xue, Yan Han, Hamid Baniasadi, Weizhong Zeng, Jimin Pei, Nick V Grishin, Junmei Wang, Benjamin P Tu, Youxing Jiang
Published 2021-08-01

Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2

by Jiajie Diao, Jacqueline Burré, Sandro Vivona, Daniel J Cipriano, Manu Sharma, Minjoung Kyoung, Thomas C Südhof, Axel T Brunger
Published 2013-04-01

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells

by Ramiro Nández, Daniel M Balkin, Mirko Messa, Liang Liang, Summer Paradise, Heather Czapla, Marco Y Hein, James S Duncan, Matthias Mann, Pietro De Camilli
Published 2014-08-01

In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system

by Lori Glenwinkel, Seth R Taylor, Kasper Langebeck-Jensen, Laura Pereira, Molly B Reilly, Manasa Basavaraju, Ibnul Rafi, Eviatar Yemini, Roger Pocock, Nenad Sestan, Marc Hammarlund, David M Miller III, Oliver Hobert
Published 2021-06-01

Kv1.1 channels regulate early postnatal neurogenesis in mouse hippocampus via the TrkB signaling pathway

by Shu-Min Chou, Ke-Xin Li, Ming-Yueh Huang, Chao Chen, Yuan-Hung Lin King, Grant Guangnan Li, Wei Zhou, Chin Fen Teo, Yuh Nung Jan, Lily Yeh Jan, Shi-Bing Yang
Published 2021-05-01

S-cone photoreceptors in the primate retina are functionally distinct from L and M cones

by Jacob Baudin, Juan M Angueyra, Raunak Sinha, Fred Rieke
Published 2019-01-01