Critical roles of ARHGAP36 as a signal transduction mediator of Shh pathway in lateral motor columnar specification

by Heejin Nam, Shin Jeon, Hyejin An, Jaeyoung Yoo, Hyo-Jong Lee, Soo-Kyung Lee, Seunghee Lee
Published 2019-07-01

A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability

by Jiang Liu, Ying Wang, Lizhi Song, Linghua Zeng, Weiwei Yi, Ting Liu, Huanzhen Chen, Miao Wang, Zhenyu Ju, Yu-Sheng Cong
Published 2017-01-01

Critical role of the HDAC6–cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect

by Kahia Messaoudi, Ashfaq Ali, Rameez Ishaq, Alberta Palazzo, Dominika Sliwa, Olivier Bluteau, Sylvie Souquère, Delphine Muller, Khadija M. Diop, Philippe Rameau, Valérie Lapierre, Jean-Pierre Marolleau, Patrick Matthias, Isabelle Godin, Gérard Pierron, Steven G. Thomas, Stephen P. Watson, Nathalie Droin, William Vainchenker, Isabelle Plo, Hana Raslova, Najet Debili
Published 2017-11-01

PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation

by Yuji Nagai, Erika Kikuchi, Walter Lerchner, Ken-ichi Inoue, Bin Ji, Mark A. G. Eldridge, Hiroyuki Kaneko, Yasuyuki Kimura, Arata Oh-Nishi, Yukiko Hori, Yoko Kato, Toshiyuki Hirabayashi, Atsushi Fujimoto, Katsushi Kumata, Ming-Rong Zhang, Ichio Aoki, Tetsuya Suhara, Makoto Higuchi, Masahiko Takada, Barry J. Richmond, Takafumi Minamimoto
Published 2016-12-01

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis

by Dong-Hyun Kim, Sanghoon Kwon, Sangwon Byun, Zhen Xiao, Sean Park, Shwu-Yuan Wu, Cheng-Ming Chiang, Byron Kemper, Jongsook Kim Kemper
Published 2016-07-01

Endomucin prevents leukocyte–endothelial cell adhesion and has a critical role under resting and inflammatory conditions

by Alisar Zahr, Pilar Alcaide, Jinling Yang, Alexander Jones, Meredith Gregory, Nathaniel G. dela Paz, Sunita Patel-Hett, Tania Nevers, Adarsha Koirala, Francis W. Luscinskas, Magali Saint-Geniez, Bruce Ksander, Patricia A. D’Amore, Pablo Argüeso
Published 2016-02-01

Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses

by Jialong Yang, Xingguang Lin, Yun Pan, Jinli Wang, Pengcheng Chen, Hongxiang Huang, Hai-Hui Xue, Jimin Gao, Xiao-Ping Zhong
Published 2016-09-01

Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection

by Carolina G. O. Lucas, Jamil Z. Kitoko, Fabricio M. Ferreira, Vinicius G. Suzart, Michelle P. Papa, Sharton V. A. Coelho, Cecilia B. Cavazzoni, Heitor A. Paula-Neto, Priscilla C. Olsen, Akiko Iwasaki, Renata M. Pereira, Pedro M. Pimentel-Coelho, Andre M. Vale, Luciana B. de Arruda, Marcelo T. Bozza
Published 2018-08-01

SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix

by Masatoshi Fukuda, Tatsuya Yoshizawa, Md. Fazlul Karim, Shihab U. Sobuz, Wataru Korogi, Daiki Kobayasi, Hiroki Okanishi, Masayoshi Tasaki, Katsuhiko Ono, Tomohiro Sawa, Yoshifumi Sato, Mami Chirifu, Takeshi Masuda, Teruya Nakamura, Hironori Tanoue, Kazuhisa Nakashima, Yoshihiro Kobashigawa, Hiroshi Morioka, Eva Bober, Sumio Ohtsuki, Yuriko Yamagata, Yukio Ando, Yuichi Oike, Norie Araki, Shu Takeda, Hiroshi Mizuta, Kazuya Yamagata
Published 2018-07-01

Correction: Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

by Koji Onomoto, Michihiko Jogi, Ji-Seung Yoo, Ryo Narita, Shiho Morimoto, Azumi Takemura, Suryaprakash Sambhara, Atushi Kawaguchi, Suguru Osari, Kyosuke Nagata, Tomoh Matsumiya, Hideo Namiki, Mitsutoshi Yoneyama, Takashi Fujita
Published 2013-01-01

Correction: Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

by Koji Onomoto, Michihiko Jogi, Ji-Seung Yoo, Ryo Narita, Shiho Morimoto, Azumi Takemura, Suryaprakash Sambhara, Atushi Kawaguchi, Suguru Osari, Kyosuke Nagata, Tomoh Matsumiya, Hideo Namiki, Mitsutoshi Yoneyama, Takashi Fujita
Published 2012-01-01

Comparative genomic analysis reveals a critical role of de novo nucleotide biosynthesis for Saccharomyces cerevisiae virulence.

by Roberto Pérez-Torrado, Silvia Llopis, Benedetta Perrone, Rocío Gómez-Pastor, Bernhard Hube, Amparo Querol
Published 2015-01-01

Intricacies of GABA_A Receptor Function: The Critical Role of the β3 Subunit in Norm and Pathology

by Sergey A. Menzikov, Sergey G. Morozov, Aslan A. Kubatiev
Published 2021-02-01

Calpain-1 and Calpain-2 in the Brain: New Evidence for a Critical Role of Calpain-2 in Neuronal Death

by Yubin Wang, Yan Liu, Xiaoning Bi, Michel Baudry
Published 2020-12-01

Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome

by Lee Shaashua, Anabel Eckerling, Boaz Israeli, Gali Yanovich, Ella Rosenne, Suzana Fichman-Horn, Ido Ben Zvi, Liat Sorski, Rita Haldar, Ronit Satchi-Fainaro, Tamar Geiger, Erica K. Sloan, Shamgar Ben-Eliyahu
Published 2020-11-01

Critical role of molecular test in early diagnosis of gastric tuberculosis: a rare case report and review of literature

by Jun Ma, Hongyun Yin, Huikang Xie
Published 2019-07-01

The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation

by Yiting Wang, Hailong Wang, Zhengwei Yan, Guohua Li, Guohui Hu, Hong Zhang, Dengliang Huang, Yao Wang, Xiang Zhang, Yehong Yan, Quqin Lu, Minzhang Cheng, Shiwen Luo
Published 2020-07-01

Sequence variations of ACVRL1 play a critical role in hepatic vascular malformations in hereditary hemorrhagic telangiectasia

by Sophie Giraud, Claire Bardel, Sophie Dupuis-Girod, Marie-France Carette, Brigitte Gilbert-Dussardier, Sophie Riviere, Jean-Christophe Saurin, Mélanie Eyries, Sylvie Patri, Evelyne Decullier, Alain Calender, Gaëtan Lesca
Published 2020-09-01

CircularRNA_104670 plays a critical role in intervertebral disc degeneration by functioning as a ceRNA

by Jian Song, Hong-Li Wang, Ke-Han Song, Zhi-Wen Ding, Hai-Lian Wang, Xiao-Sheng Ma, Fei-Zhou Lu, Xin-Lei Xia, Ying-Wei Wang, Fei-Zou, Jian-Yuan Jiang
Published 2018-08-01

Prostaglandin F2α synthase in Trypanosoma cruzi plays critical roles in oxidative stress and susceptibility to benznidazole

by Paola García-Huertas, Ana María Mejía-Jaramillo, Carlos Renato Machado, Anna Cláudia Guimarães, Omar Triana-Chávez
Published 2017-01-01