BRD4 Phosphorylation Regulates HPV E2-Mediated Viral Transcription, Origin Replication, and Cellular MMP-9 Expression

by Shwu-Yuan Wu, Dawn Sijin Nin, A-Young Lee, Scott Simanski, Thomas Kodadek, Cheng-Ming Chiang
Published 2016-08-01

BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination

by Hyunkyung Jung, Jinjing Chen, Xiangming Hu, Hao Sun, Shwu-Yuan Wu, Cheng-Ming Chiang, Byron Kemper, Lin-Feng Chen, Jongsook Kim Kemper
Published 2021-01-01

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis

by Dong-Hyun Kim, Sanghoon Kwon, Sangwon Byun, Zhen Xiao, Sean Park, Shwu-Yuan Wu, Cheng-Ming Chiang, Byron Kemper, Jongsook Kim Kemper
Published 2016-07-01

Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA.

by Nozomi Sakakibara, Dan Chen, Moon Kyoo Jang, Dong Wook Kang, Hans F Luecke, Shwu-Yuan Wu, Cheng-Ming Chiang, Alison A McBride
Published 2013-01-01

BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis

by Thomas C. Roberts, Usue Etxaniz, Alessandra Dall’Agnese, Shwu-Yuan Wu, Cheng-Ming Chiang, Paul E. Brennan, Matthew J. A. Wood, Pier Lorenzo Puri
Published 2017-07-01

Papillomavirus-Associated Tumor Formation Critically Depends on c-Fos Expression Induced by Viral Protein E2 and Bromodomain Protein Brd4.

by Maria Delcuratolo, Jasmin Fertey, Markus Schneider, Johanna Schuetz, Natalie Leiprecht, Benjamin Hudjetz, Stephan Brodbeck, Silke Corall, Marcel Dreer, Roxana Michaela Schwab, Martin Grimm, Shwu-Yuan Wu, Frank Stubenrauch, Cheng-Ming Chiang, Thomas Iftner
Published 2016-01-01