Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease

by Jörn F. Ziegler, Chotima Böttcher, Marilena Letizia, Cansu Yerinde, Hao Wu, Inka Freise, Yasmina Rodriguez-Sillke, Ani K. Stoyanova, Martin E. Kreis, Patrick Asbach, Desiree Kunkel, Josef Priller, Ioannis Anagnostopoulos, Anja A. Kühl, Konstanze Miehle, Michael Stumvoll, Florian Tran, Broder Fredrich, Michael Forster, Andre Franke, Christian Bojarski, Rainer Glauben, Britt-Sabina Löscher, Britta Siegmund, Carl Weidinger
Published 2019-12-01

Sensing Acute Cellular Rejection in Liver Transplant Patients Using Liver-Derived Extracellular Particles: A Prospective, Observational Study

by Kaan Kamali, Moritz Schmelzle, Can Kamali, Philipp Brunnbauer, Katrin Splith, Annekatrin Leder, Nadja Berndt, Karl-Herbert Hillebrandt, Karl-Herbert Hillebrandt, Nathanael Raschzok, Linda Feldbrügge, Matthäus Felsenstein, Matthäus Felsenstein, Joseph Gaßner, Paul Ritschl, Paul Ritschl, Georg Lurje, Wenzel Schöning, Christian Benzing, Johann Pratschke, Felix Krenzien, Felix Krenzien
Published 2021-05-01

The effect of a deteriorated architecture of the lacunocanalicular network on the organization and mineralization of the extracellular matrix

by Andreas Roschger, Alexander F. van Tol, Michael Thelen, Anne Seliger, Haisheng Yang, Wing Lee Chan, Tobias Thiele, Paul Roschger, Georg N. Duda, Paul Zaslansky, Uwe Kornak, Bettina M. Willie, Richard Weinkamer
Published 2020-10-01

Critical Illness and Systemic Inflammation Are Key Risk Factors of Severe Acute Kidney Injury in Patients With COVID-19

by Jan-Hendrik B. Hardenberg, Helena Stockmann, Annette Aigner, Inka Gotthardt, Philipp Enghard, Christian Hinze, Felix Balzer, Danilo Schmidt, Daniel Zickler, Jan Kruse, Roland Körner, Miriam Stegemann, Thomas Schneider, Michael Schumann, Holger Müller-Redetzky, Stefan Angermair, Klemens Budde, Steffen Weber-Carstens, Martin Witzenrath, Sascha Treskatsch, Britta Siegmund, Claudia Spies, Norbert Suttorp, Geraldine Rauch, Kai-Uwe Eckardt, Kai M. Schmidt-Ott
Published 2021-04-01

Compromised Bone Healing in Aged Rats Is Associated With Impaired M2 Macrophage Function

by Julia Löffler, Julia Löffler, F. Andrea Sass, F. Andrea Sass, Sebastian Filter, Alexander Rose, Agnes Ellinghaus, Agnes Ellinghaus, Georg N. Duda, Georg N. Duda, Anke Dienelt, Anke Dienelt
Published 2019-10-01

Uncovering convolutional neural network decisions for diagnosing multiple sclerosis on conventional MRI using layer-wise relevance propagation

by Fabian Eitel, Emily Soehler, Judith Bellmann-Strobl, Alexander U. Brandt, Klemens Ruprecht, René M. Giess, Joseph Kuchling, Susanna Asseyer, Martin Weygandt, John-Dylan Haynes, Michael Scheel, Friedemann Paul, Kerstin Ritter
Published 2019-01-01

Evaluation of PEEP and prone positioning in early COVID-19 ARDS

by Mirja Mittermaier, Philipp Pickerodt, Florian Kurth, Laure Bosquillon de Jarcy, Alexander Uhrig, Carmen Garcia, Felix Machleidt, Panagiotis Pergantis, Susanne Weber, Yaosi Li, Astrid Breitbart, Felix Bremer, Philipp Knape, Marc Dewey, Felix Doellinger, Steffen Weber-Carstens, Arthur S. Slutsky, Wolfgang M. Kuebler, Norbert Suttorp, Holger Müller-Redetzky
Published 2020-11-01

Exploratory Investigation of Intestinal Function and Bacterial Translocation After Focal Cerebral Ischemia in the Mouse

by Naoki Oyama, Naoki Oyama, Katarzyna Winek, Katarzyna Winek, Katarzyna Winek, Priscilla Bäcker-Koduah, Priscilla Bäcker-Koduah, Tian Zhang, Tian Zhang, Claudia Dames, Martina Werich, Olivia Kershaw, Christian Meisel, Andreas Meisel, Andreas Meisel, Andreas Meisel, Andreas Meisel, Ulrich Dirnagl, Ulrich Dirnagl, Ulrich Dirnagl, Ulrich Dirnagl, Ulrich Dirnagl, Ulrich Dirnagl
Published 2018-11-01

Killer-like receptors and GPR56 progressive expression defines cytokine production of human CD4+ memory T cells

by Kim-Long Truong, Stephan Schlickeiser, Katrin Vogt, David Boës, Katarina Stanko, Christine Appelt, Mathias Streitz, Gerald Grütz, Nadja Stobutzki, Christian Meisel, Christina Iwert, Stefan Tomiuk, Julia K. Polansky, Andreas Pascher, Nina Babel, Ulrik Stervbo, Igor Sauer, Undine Gerlach, Birgit Sawitzki
Published 2019-05-01

Single-cell analysis based dissection of clonality in myelofibrosis

by Elena Mylonas, Kenichi Yoshida, Mareike Frick, Kaja Hoyer, Friederike Christen, Jaspal Kaeda, Matthias Obenaus, Daniel Noerenberg, Cornelius Hennch, Willy Chan, Yotaro Ochi, Yuichi Shiraishi, Yusuke Shiozawa, Thorsten Zenz, Christopher C. Oakes, Birgit Sawitzki, Michaela Schwarz, Lars Bullinger, Philipp le Coutre, Matthew J. J. Rose-Zerilli, Seishi Ogawa, Frederik Damm
Published 2020-01-01

POS-053 90-day post-hospital follow-up in survivors after COVID-19-associated acute kidney injury requiring kidney replacement therapy

by H. Stockmann, J.H.B. Hardenberg, C. Hinze, A. Aigner, G. Inka, B. Stier, K.U. Eckardt, K.M. Schmidt-Ott, P. Enghard
Published 2021-04-01

Long-Term Signs of T Cell and Myeloid Cell Activation After Intestinal Transplantation With Cellular Rejections Contributing to Further Increase of CD16+ Cell Subsets

by Nadja Stobutzki, Stephan Schlickeiser, Stephan Schlickeiser, Mathias Streitz, Katarina Stanko, Kim-Long Truong, Levent Akyuez, Levent Akyuez, Katrin Vogt, Christine Appelt, Andreas Pascher, Olga Blau, Undine A. Gerlach, Birgit Sawitzki, Birgit Sawitzki
Published 2019-05-01

CD4+ T Cell Dependent B Cell Recovery and Function After Autologous Hematopoietic Stem Cell Transplantation

by Clarissa Heck, Sophie Steiner, Eva M. Kaebisch, Eva M. Kaebisch, Marco Frentsch, Friedrich Wittenbecher, Friedrich Wittenbecher, Carmen Scheibenbogen, Carmen Scheibenbogen, Leif G. Hanitsch, Axel Nogai, Philipp le Coutre, Lars Bullinger, Lars Bullinger, Lars Bullinger, Lars Bullinger, Igor-Wolfgang Blau, Il-Kang Na, Il-Kang Na, Il-Kang Na, Il-Kang Na, Il-Kang Na
Published 2021-09-01

Episodic Hypoxia Promotes Defence Against Cellular Stress

by Vicky Heß, Mumtaz Kasim, Susanne Mathia, Pontis B. Persson, Christian Rosenberger, Michael Fähling
Published 2019-04-01

Altered Coupling of Psychological Relaxation and Regional Volume of Brain Reward Areas in Multiple Sclerosis

by Katharina Wakonig, Fabian Eitel, Fabian Eitel, Kerstin Ritter, Kerstin Ritter, Stefan Hetzer, Tanja Schmitz-Hübsch, Tanja Schmitz-Hübsch, Judith Bellmann-Strobl, Judith Bellmann-Strobl, John-Dylan Haynes, John-Dylan Haynes, John-Dylan Haynes, Alexander U. Brandt, Alexander U. Brandt, Stefan M. Gold, Stefan M. Gold, Stefan M. Gold, Friedemann Paul, Friedemann Paul, Friedemann Paul, Martin Weygandt, Martin Weygandt
Published 2020-10-01

Continuous Blood Glucose Monitoring Reveals Enormous Circadian Variations in Pregnant Diabetic Rats

by Michaela Golic, Michaela Golic, Michaela Golic, Michaela Golic, Michaela Golic, Kristin Kräker, Kristin Kräker, Kristin Kräker, Kristin Kräker, Kristin Kräker, Caroline Fischer, Caroline Fischer, Caroline Fischer, Caroline Fischer, Natalia Alenina, Natalia Alenina, Natalia Alenina, Nadine Haase, Nadine Haase, Nadine Haase, Nadine Haase, Nadine Haase, Florian Herse, Florian Herse, Florian Herse, Florian Herse, Till Schütte, Till Schütte, Wolfgang Henrich, Dominik N. Müller, Dominik N. Müller, Dominik N. Müller, Dominik N. Müller, Dominik N. Müller, Andreas Busjahn, Michael Bader, Michael Bader, Michael Bader, Michael Bader, Ralf Dechend, Ralf Dechend, Ralf Dechend, Ralf Dechend
Published 2018-05-01

Molecular MR Imaging of Prostate Cancer

by Avan Kader, Julia Brangsch, Jan O. Kaufmann, Jing Zhao, Dilyana B. Mangarova, Jana Moeckel, Lisa C. Adams, Ingolf Sack, Matthias Taupitz, Bernd Hamm, Marcus R. Makowski
Published 2021-12-01

Olfactory and Gustatory Dysfunction in Patients With Autoimmune Encephalitis

by Rohat Geran, Rohat Geran, Rohat Geran, Florian C. Uecker, Harald Prüss, Harald Prüss, Karl Georg Haeusler, Friedemann Paul, Friedemann Paul, Friedemann Paul, Klemens Ruprecht, Klemens Ruprecht, Lutz Harms, Lutz Harms, Felix A. Schmidt, Felix A. Schmidt, Felix A. Schmidt, Felix A. Schmidt
Published 2019-05-01

Lateral geniculate nucleus volume changes after optic neuritis in neuromyelitis optica: A longitudinal study

by Athina Papadopoulou, Frederike C. Oertel, Claudia Chien, Joseph Kuchling, Hanna G. Zimmermann, Nadja Siebert, Seyedamirhosein Motamedi, Marcus D' Souza, Susanna Asseyer, Judith Bellmann-Strobl, Klemens Ruprecht, M. Mallar Chakravarty, Michael Scheel, Stefano Magon, Jens Wuerfel, Friedemann Paul, Alexander U. Brandt
Published 2021-01-01

Generation of Human CRY1 and CRY2 Knockout Cells Using Duplex CRISPR/Cas9 Technology

by Teresa Börding, Teresa Börding, Ashraf N. Abdo, Ashraf N. Abdo, Ashraf N. Abdo, Bert Maier, Bert Maier, Christian Gabriel, Christian Gabriel, Achim Kramer, Achim Kramer
Published 2019-05-01