Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis

by Andrea Mencarelli, Hanif Javanmard Khameneh, Jan Fric, Maurizio Vacca, Sary El Daker, Baptiste Janela, Jing Ping Tang, Sabrina Nabti, Akhila Balachander, Tong Seng Lim, Florent Ginhoux, Paola Ricciardi-Castagnoli, Alessandra Mortellaro
Published 2018-03-01

Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723

by Swati Sinha, Choy-Eng Nge, Chung Yan Leong, Veronica Ng, Sharon Crasta, Mohammad Alfatah, Falicia Goh, Kia-Ngee Low, Huibin Zhang, Prakash Arumugam, Alexander Lezhava, Swaine L. Chen, Yoganathan Kanagasundaram, Siew Bee Ng, Frank Eisenhaber, Birgit Eisenhaber
Published 2019-05-01

Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy

by Ruth Jinfen Chai, Hendrikje Werner, Peter Yiqing Li, Yin Loon Lee, Khaing Thet Nyein, Irina Solovei, Tuan Danh Anh Luu, Bhavya Sharma, Raju Navasankari, Martina Maric, Lois Yu En Sim, Ying Jie Loh, Edita Aliwarga, Jason Wen Long Cheong, Alexandre Chojnowski, Matias Ilmari Autio, Yu Haiyang, Kenneth Kian Boon Tan, Choong Tat Keng, Shi Ling Ng, Wei Leong Chew, Michael Ferenczi, Brian Burke, Roger Sik Yin Foo, Colin L. Stewart
Published 2021-08-01

Author Correction: Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury

by Carla Claser, Samantha Yee Teng Nguee, Akhila Balachander, Shanshan Wu Howland, Etienne Becht, Bavani Gunasegaran, Siddesh V. Hartimath, Audrey W. Q. Lee, Jacqueline Theng Theng Ho, Chee Bing Ong, Evan W. Newell, Julian Goggi, Lai Guan Ng, Laurent Renia
Published 2019-11-01

PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis

by Slim Mzoughi, Jia Yi Fong, David Papadopoli, Cheryl M. Koh, Laura Hulea, Paolo Pigini, Federico Di Tullio, Giuseppe Andreacchio, Michal Marek Hoppe, Heike Wollmann, Diana Low, Matias J. Caldez, Yanfen Peng, Denis Torre, Julia N. Zhao, Oro Uchenunu, Gabriele Varano, Corina-Mihaela Motofeanu, Manikandan Lakshmanan, Shun Xie Teo, Cheng Mun Wun, Giovanni Perini, Soo Yong Tan, Chee Bing Ong, Muthafar Al-Haddawi, Ravisankar Rajarethinam, Susan Swee-Shan Hue, Soon Thye Lim, Choon Kiat Ong, Dachuan Huang, Siok-Bian Ng, Emily Bernstein, Dan Hasson, Keng Boon Wee, Philipp Kaldis, Anand Jeyasekharan, David Dominguez-sola, Ivan Topisirovic, Ernesto Guccione
Published 2020-07-01

Comprehensive mapping of SARS-CoV-2 interactions in vivo reveals functional virus-host interactions

by Siwy Ling Yang, Louis DeFalco, Danielle E. Anderson, Yu Zhang, Jong Ghut Ashley Aw, Su Ying Lim, Xin Ni Lim, Kiat Yee Tan, Tong Zhang, Tanu Chawla, Yan Su, Alexander Lezhava, Andres Merits, Lin-Fa Wang, Roland G. Huber, Yue Wan
Published 2021-08-01

Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury

by Carla Claser, Samantha Yee Teng Nguee, Akhila Balachander, Shanshan Wu Howland, Etienne Becht, Bavani Gunasegaran, Siddesh V. Hartimath, Audrey W. Q. Lee, Jacqueline Theng Theng Ho, Chee Bing Ong, Evan W. Newell, Julian Goggi, Lai Guan Ng, Laurent Renia
Published 2019-09-01

Insights into Antibody-Mediated Alphavirus Immunity and Vaccine Development Landscape

by Anthony Torres-Ruesta, Rhonda Sin-Ling Chee, Lisa F. P. Ng
Published 2021-04-01

NUCKS Is a Positive Transcriptional Regulator of Insulin Signaling

by Beiying Qiu, Xiaohe Shi, Ee Tsin Wong, Joy Lim, Marco Bezzi, Diana Low, Qiling Zhou, Semih Can Akıncılar, Manikandan Lakshmanan, Hannah L.F. Swa, Jill Mae Lan Tham, Jayantha Gunaratne, Kenneth K.Y. Cheng, Wanjin Hong, Karen S.L. Lam, Masahito Ikawa, Ernesto Guccione, Aimin Xu, Weiping Han, Vinay Tergaonkar
Published 2014-06-01

N95 respirator decontamination: a study in reusability

by C.-G. Wang, Z. Li, S. Liu, C.T. Ng, M. Marzuki, P.S. Jeslyn Wong, B. Tan, A. Lee, C.F. Hui Lim, P. Bifani, Z. Fang, J.C. Ching Wong, Y.X. Setoh, Y.Y. Yang, C.H. Mun, S.Z. Fiona Phua, W.Q. Lim, L. Lin, A.R. Cook, H. Tanoto, L.-C. Ng, A. Singhal, Y.W. Leong, X.J. Loh
Published 2021-09-01

Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway

by Hassen Kared, Shu Wen Tan, Mai Chan Lau, Marion Chevrier, Crystal Tan, Wilson How, Glenn Wong, Marie Strickland, Benoit Malleret, Amanda Amoah, Karolina Pilipow, Veronica Zanon, Naomi Mc Govern, Josephine Lum, Jin Miao Chen, Bernett Lee, Maria Carolina Florian, Hartmut Geiger, Florent Ginhoux, Ezequiel Ruiz-Mateos, Tamas Fulop, Reena Rajasuriar, Adeeba Kamarulzaman, Tze Pin Ng, Enrico Lugli, Anis Larbi
Published 2020-02-01

CD103+ Dendritic Cells Control Th17 Cell Function in the Lung

by Teresa Zelante, Alicia Yoke Wei Wong, Tang Jing Ping, Jinmiao Chen, Hermi R. Sumatoh, Elena Viganò, Yu Hong Bing, Bernett Lee, Francesca Zolezzi, Jan Fric, Evan W. Newell, Alessandra Mortellaro, Michael Poidinger, Paolo Puccetti, Paola Ricciardi-Castagnoli
Published 2015-09-01

Vertical Silicon Nanowire Platform for Low Power Electronics and Clean Energy Applications

by D.-L. Kwong, X. Li, Y. Sun, G. Ramanathan, Z. X. Chen, S. M. Wong, Y. Li, N. S. Shen, K. Buddharaju, Y. H. Yu, S. J. Lee, N. Singh, G. Q. Lo
Published 2012-01-01

CMOS-compatible a-Si metalenses on a 12-inch glass wafer for fingerprint imaging

by Hu Ting, Zhong Qize, Li Nanxi, Dong Yuan, Xu Zhengji, Fu Yuan Hsing, Li Dongdong, Bliznetsov Vladimir, Zhou Yanyan, Lai Keng Heng, Lin Qunying, Zhu Shiyang, Singh Navab
Published 2020-02-01

Mapping of γ/δ T cells reveals Vδ2+ T cells resistance to senescenceResearch in context

by Weili Xu, Gianni Monaco, Eleanor Huijin Wong, Wilson Lek Wen Tan, Hassen Kared, Yannick Simoni, Shu Wen Tan, Wilson Zhi Yong How, Crystal Tze Ying Tan, Bernett Teck Kwong Lee, Daniel Carbajo, Srinivasan K.G., Ivy Chay Huang Low, Esther Wing Hei Mok, Shihui Foo, Josephine Lum, Hong Liang Tey, Wee Ping Tan, Michael Poidinger, Evan Newell, Tze Pin Ng, Roger Foo, Arne N. Akbar, Tamas Fülöp, Anis Larbi
Published 2019-01-01

Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection

by Yi-Hao Chan, Yi-Hao Chan, Teck-Hui Teo, Anthony Torres-Ruesta, Anthony Torres-Ruesta, Siddesh V. Hartimath, Rhonda Sin-Ling Chee, Shivashankar Khanapur, Fui Fong Yong, Boominathan Ramasamy, Peter Cheng, Ravisankar Rajarethinam, Edward G. Robins, Edward G. Robins, Julian L. Goggi, Fok-Moon Lum, Guillaume Carissimo, Laurent Rénia, Laurent Rénia, Lisa F. P. Ng, Lisa F. P. Ng, Lisa F. P. Ng, Lisa F. P. Ng
Published 2020-05-01

NLRP10 Enhances CD4+ T-Cell-Mediated IFNγ Response via Regulation of Dendritic Cell-Derived IL-12 Release

by Maurizio Vacca, Maurizio Vacca, Julia Böhme, Lia Paola Zambetti, Hanif Javanmard Khameneh, Bhairav S. Paleja, Federica Laudisi, Adrian W. S. Ho, Kurt Neo, Keith Weng Kit Leong, Mardiana Marzuki, Bernett Lee, Michael Poidinger, Laura Santambrogio, Liana Tsenova, Francesca Zolezzi, Gennaro De Libero, Gennaro De Libero, Amit Singhal, Amit Singhal, Alessandra Mortellaro, Alessandra Mortellaro
Published 2017-11-01

Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits

by Julia Böhme, Nuria Martinez, Shamin Li, Andrea Lee, Mardiana Marzuki, Anteneh Mehari Tizazu, David Ackart, Jessica Haugen Frenkel, Alexandra Todd, Ekta Lachmandas, Josephine Lum, Foo Shihui, Tze Pin Ng, Bernett Lee, Anis Larbi, Mihai G. Netea, Randall Basaraba, Reinout van Crevel, Evan Newell, Hardy Kornfeld, Amit Singhal
Published 2020-10-01

FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression

by Kia Joo Puan, Boris San Luis, Nurhashikin Yusof, Dilip Kumar, Anand Kumar Andiappan, Wendy Lee, Samanta Cajic, Dragana Vuckovic, Jing De Chan, Tobias Döllner, Han Wei Hou, Yunxuan Jiang, Chao Tian, the 23andMe Research Team, Erdmann Rapp, Michael Poidinger, De Yun Wang, Nicole Soranzo, Bernett Lee, Olaf Rötzschke
Published 2021-07-01

First‐in‐Human, Healthy Volunteers Integrated Protocol of ETC‐206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug

by Vincenzo Teneggi, Veronica Novotny‐Diermayr, Lay Hoon Lee, Maryam Yasin, Pauline Yeo, Kantharaj Ethirajulu, Sylvia Bong Hwa Gan, Stephanie E. Blanchard, Ranjani Nellore, Dhananjay N. Umrani, Roberto Gomeni, Darren Lim Wan Teck, Greg Li, Qing Shu Lu, Yang Cao, Alex Matter
Published 2020-01-01