protein determination Article 15 human 13 Humans 11 controlled study 11 female 8 nonhuman 8 male 7 unclassified drug 7 Male 6 human cell 6 Animals 5 Female 5 adult 5 blood 5 protein blood level 5 protein expression 5 protein function 5 sensitivity and specificity 5 Biomarkers 4 animal 4 animal experiment 4 animal tissue 4 biological marker 4 drug effect 4 middle aged 4 procedures 4 Adult 3 Mice 3 Middle Aged 3