Animals Antimalarial Antimalarials Article Disease Models, Animal Dose-Response Relationship, Drug Endophytic Gancidin W In vivo Institute for Cancer Research mouse Malaria Male Mice Mice, Inbred ICR Molecular Conformation Parasitic Sensitivity Tests Piperazines Plasmodium berghei Plasmodium berghei infection Shorea ovalis Streptomyces alanine aminotransferase alanine aminotransferase blood level alkaline phosphatase alkaline phosphatase blood level animal animal experiment animal model animal tissue antimalarial activity