AMPK signaling 1 B Raf kinase 1 Note 1 STAT3 protein 1 STAT5 protein 1 STAT5a protein 1 STAT5b protein 1 biological marker 1 cancer growth 1 cancer immunotherapy 1 cancer inhibition 1 cell adhesion 1 cell invasion 1 cell migration 1 cutaneous melanoma cutaneous melanoma cell line 1 extracellular matrix 1 focal adhesion kinase 1 gene activation 1 human 1 hydroxymethylglutaryl coenzyme A reductase kinase 1 immune checkpoint inhibitor 1 immune evasion 1 loss of function mutation 1 metastatic melanoma 1 microsatellite instability 1 nonhuman 1 oncogene N ras 1 pathogenesis 1 phenotype 1