3D reconstruction 1 Angular orientation 1 Automated detection 1 Autopicking 1 Convolution 1 Convolutional neural network 1 Convolutional neural networks 1 Cryo-electron micrographs 1 CryoEM 1 Cryoelectron Microscopy 1 Deep learning 1 Different particle sizes 1 Electron microscopy 1 Electrons 1 Evaluation metrics 1 Image Processing, Computer-Assisted 1 Image reconstruction 1 Image segmentation 1 Imaging, Three-Dimensional 1 Low signal-to-noise ratio 1 Neural Networks, Computer 1 Particle picking Particle size 1 Particle size analysis 1 Performance metrics 1 Probability density function 1 Proteins 1 Regression 1 Regression Analysis 1 Signal to noise ratio 1