Mechanisms Underlying the Anti-Inflammatory Effects of Clinacanthus nutans Lindau Extracts: Inhibition of Cytokine Production and Toll-Like Receptor-4 Activation

Mechanisms Underlying the Anti-Inflammatory Effects of Clinacanthus nutans Lindau Extracts: Inhibition of Cytokine Production and Toll-Like Receptor-4 Activation

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Clinacanthus nutans has had a long history of use in folk medicine in Malaysia and Southeast Asia; mostly in the relief of inflammatory conditions. In this study, we investigated the effects of different extracts of C. nutans upon lipopolysaccharide (LPS) induced inflammation in order to identify it...

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Bibliographic Details
Main Authors: Chin, SY (Author), Ismail, NH (Author), Kho, MT (Author), Lim, ESH (Author), Mai, CW (Author), Shaari, K (Author), Yap, KSI (Author), Yusoff, K (Author)
Format: Article
Language:English
Published: 2016
Subjects:
anti-inflammatory agents
CELLS
Clinacanthus nutans
EXPRESSION
INFLAMMATION
LIPOPOLYSACCHARIDE-MEDIATED INDUCTION
LPS
macrophages
MURINE MACROPHAGES
NF-KAPPA-B
NITRIC-OXIDE SYNTHASE
RAW 264.7 MACROPHAGES
TLR-4
Toll-like receptor 4
total flavonoid content
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