Mutational analysis of CYP2C8 in hypertensive patients using denaturing high performance liquid chromatography

What is known and Objective: CYP2C8 is involved in the cytochrome P450 (CYP) epoxygenase pathway. Arachidonic acid metabolites such as epoxyeicosatrienenoic acids and hydroxyeicosatetrenoic acids, produced may have a role in hypertension. We aimed to develop a medium through-put method for screening...

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Bibliographic Details
Main Authors: Ismail, R (Author), Salleh, MZ (Author), Teh, LK (Author), Zahri, MK (Author), Zakaria, ZA (Author)
Format: Article
Language:English
Series:JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
Online Access:View Fulltext in Publisher