Closely linked cis-acting modifier of expansion of the CGG repeat in high risk FMR1 haplotypes
In its expanded form, the fragile X triplet repeat at Xq27.3 gives rise to the most common form of inherited mental retardation, fragile X syndrome. This high population frequency persists despite strong selective pressure against mutation-bearing chromosomes. Males carrying the full mutation rarely...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2007-12-02.
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| Subjects: | |
| Online Access: | Get fulltext |