Innate immune collectin surfactant protein D enhances the clearance of DNA by macrophages and minimizes anti-DNA antibody generation
Dying microbes and necrotic cells release highly viscous DNA that induces inflammation and septic shock, and apoptotic cells display DNA, a potential autoantigen, on their surfaces. However, innate immune proteins that mediate the clearance of free DNA and surface DNA-containing cells are not clearl...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2005-06-01.
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| Subjects: | |
| Online Access: | Get fulltext |