Plasticity of empty major histocompatibility complex class I molecules determines peptide-selector function.

Major histocompatibility complex class I (MHC I) proteins provide protection from intracellular pathogens and cancer via each of a cell's MHC I molecules binding and presenting a peptide to cytotoxic T lymphocytes. MHC I genes are highly polymorphic and can have significant diversity, with poly...

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Bibliographic Details
Main Authors: van Hateren, Andy (Author), Bailey, Alistair (Author), Werner, Jörn M. (Author), Elliott, Tim (Author)
Format: Article
Language:English
Published: 2015-12.
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