Advanced glycation end-products reduce collagen molecular sliding to affect collagen fibril damage mechanisms but not stiffness
Advanced glycation end-products (AGE) contribute to age-related connective tissue damage and functional deficit. The documented association between AGE formation on collagens and the correlated progressive stiffening of tissues has widely been presumed causative, despite the lack of mechanistic unde...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2014-11-03.
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| Subjects: | |
| Online Access: | Get fulltext |