Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled tria.

Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled tria.

Background: osteoarthritis (OA) is the fastest growing cause of disability worldwide. Current treatments for OA are severely limited and a large proportion of people with OA live in constant, debilitating pain. There is therefore an urgent need for novel treatments to reduce pain. Synovitis is highl...

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Main Authors: Kingsbury, S.R (Author), Thamanathan, P. (Author), Arden, N.K (Author), Batley, M. (Author), Birrell, M. (Author), Cocks, K. (Author), Doherty, M. (Author), Edwards, C.J (Author), Garrood, T. (Author), Grainger, A.J (Author), Green, M. (Author), Hewitt, C. (Author), Hughes, R. (Author), Moots, R. (Author), O'Neill, T.W (Author), Roddy, E. (Author), Scott, D.L (Author), Watt, F.E (Author), Torgerson, D.J (Author), Conaghan, P.G (Author)
Format: Article
Language:English
Published: 2015-03-04.
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