Cigarette smoke causes caspase-independent apoptosis of bronchial epithelial cells from asthmatic donors
Our results show that PBECs from asthmatic donors are more susceptible to CSE-induced apoptosis. This response involves AIF, which has been implicated in DNA damage and ROS-mediated cell-death. Epithelial susceptibility to CSE may contribute to the impact of environmental tobacco smoke in asthma
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2015-03-20.
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| Subjects: | |
| Online Access: | Get fulltext |