Regulation of protein stability of DNA methyltransferase 1 by post-translational modifications

DNA methylation is an important epigenetic mechanism that ensures correct gene expression and maintains genetic stability. DNA methyltransferase 1 (DNMT1) is the primary enzyme that maintains DNA methylation during replication. Dysregulation of DNMT1 is implicated in a variety of diseases. DNMT1 pro...

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Bibliographic Details
Main Authors: Scott, A. (Author), Song, J. (Author), Ewing, R. (Author), Wang, Z. (Author)
Format: Article
Language:English
Published: 2014-03.
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