The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output

The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output

Phosphoinositides (PI) are important signaling molecules in the nucleus that influence gene expression. However, if and how nuclear PI directly affects the transcriptional machinery is not known. We report that the lipid kinase PIP4K2B regulates nuclear PI5P and the expression of myogenic genes duri...

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Main Authors: Stijf-Bultsma, Yvette (Author), Sommer, Lilly (Author), Tauber, Maria (Author), Baalbaki, Mai (Author), Giardoglou, Panagiota (Author), Jones, David R. (Author), Gelato, Kathy A. (Author), van Pelt, Jason (Author), Shah, Zahid (Author), Rahnamoun, Homa (Author), Toma, Clara (Author), Anderson, Karen E. (Author), Hawkins, Philip (Author), Lauberth, Shannon M. (Author), Haramis, Anna-Pavlina G. (Author), Hart, Daniel (Author), Fischle, Wolfgang (Author), Divecha, Nullin (Author)
Format: Article
Language:English
Published: 2015-05-07.
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