Lack of a synergistic effect of a non-viral ALS gene therapy based on BDNF and a TTC fusion molecule

Significant improvements in behavioral and electrophysiological results, motoneuron survival and anti-apoptotic/survival-activated pathways were observed with BDNF-TTC treatment. However, no synergistic effect was found for this fusion molecule. Although BDNF in the fusion molecule is capable of act...

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Main Authors: Calvo, Ana C. (Author), Moreno-Igoa, María (Author), Mancuso, Renzo (Author), Manzano, Raquel (Author), Oliván, Sara (Author), Muñoz, María J. (Author), Penas, Clara (Author), Zaragoza, Pilar (Author), Navarro, Xavier (Author), Osta, Rosario (Author)
Format: Article
Language:English
Published: 2011-03.
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