Generation and trapping of ketenes in flow
Ketenes were generated by the thermolysis of alkoxyalkynes under flow conditions, and then trapped with amines and alcohols to cleanly give amides and esters. For a 10 min reaction time, temperatures of 180, 160, and 140 °C were required for >95?% conversion of EtO, iPrO, and tBuO alkoxyalkynes,...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2015-02.
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| Subjects: | |
| Online Access: | Get fulltext |