Aβ immunotherapy for Alzheimer's disease: effects on apoE and cerebral vasculopathy

Aβ immunotherapy for Alzheimer's disease (AD) results in the removal of Av plaques and increased cerebral amyloid angiopathy (CAA). In current clinical trials, amyloid-related imaging abnormalities (ARIAs), putatively due to exacerbation of CAA, are concerning side effects. We aimed to assess t...

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Bibliographic Details
Main Authors: Sakai, Kenji (Author), Boche, Delphine (Author), Carare, Roxana (Author), Johnston, David (Author), Holmes, Clive (Author), Love, Seth (Author), Nicoll, James A R (Author)
Format: Article
Language:English
Published: 2014-12-01.
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