A central role for GRB10 in regulation of islet function in man

Variants in the growth factor receptor-bound protein 10 (GRB10) gene were in a GWAS meta-analysis associated with reduced glucose-stimulated insulin secretion and increased risk of type 2 diabetes (T2D) if inherited from the father, but inexplicably reduced fasting glucose when inherited from the mo...

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Main Authors: Prokopenko, I. (Author), Poon, W. (Author), Magi, R. (Author), Prasad, B.R (Author), Salehi, S.A (Author), Almgren, P. (Author), Osmark, P. (Author), Bouatia-Naji, N. (Author), Wierup, N. (Author), Fall, T. (Author), Stancakova, A. (Author), Barker, A. (Author), Lagou, V. (Author), Osmond, Clive (Author), Xie, W. (Author), Lahti, J. (Author), Jackson, A.U (Author), Cheng, Y.C (Author), Liu, J. (Author), O'Connell, J.R (Author), Blomstedt, P.A (Author), Fadista, J. (Author), Alkayyali, S. (Author), Dayeh, T. (Author), Ahlqvist, E. (Author), Taneera, J. (Author), Lecoeur, C. (Author), Kumar, A. (Author), Hansson, O. (Author), Hansson, K. (Author), Voight, B.F (Author), Kang, H.M (Author), Levy-Marchal, C. (Author), Vatin, V. (Author), Palotie, A. (Author), Syvanen, A.C (Author), Mari, A. (Author), Weedon, M.N (Author), Loos, R.J (Author), Ong, K.K (Author), Nilsson, P. (Author), Isomaa, B. (Author), Tuomi, T. (Author), Wareham, N.J (Author), Stumvoll, M. (Author), Widen, E. (Author), Lakka, T.A (Author), Langenberg, C. (Author), Tonjes, A. (Author), Rauramaa, R. (Author), Kuusisto, J. (Author), Frayling, T.M (Author), Froguel, P. (Author), Walker, M. (Author), Eriksson, J.G (Author), Ling, C. (Author), Kovacs, P. (Author), Inglesson, E. (Author), McCarthy, M.I (Author), Shuldiner, A.R (Author), Silver, K.D (Author), Laakso, M. (Author), Groop, L. (Author), Lyssenko, V. (Author)
Format: Article
Language:English
Published: 2014-04-03.
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