Disruption of arterial perivascular drainage of amyloid-? from the brains of mice expressing the human APOE ?4 allele
Failure of elimination of amyloid-? (A?) from the brain and vasculature appears to be a key factor in the etiology of sporadic Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA). In addition to age, possession of an apolipoprotein E (APOE) ?4 allele is a strong risk factor for the d...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2012-07.
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| Subjects: | |
| Online Access: | Get fulltext |